CAJ | 학술논문

目的：探讨经直肠前列腺超声造影在前列腺癌活检中的临床应用价值。方法选择73例血清前列腺特异性抗原（PSA）≥4 ng/mL，且直肠指检阳性或经直肠超声发现可疑病灶的患者行超声造影检查，随后行超声造影异常增强区靶向穿刺+6点常规穿刺，对超声造影未见异常者行常规6点穿刺。以病理结果为对照，分析超声造影图像特征。结果以病理为标准，超声造影诊断前列腺癌的灵敏度、特异度、准确率、阳性预测值、阴性预测值分别为73.33%、93.02%、84.93%、88.00%、83.33%。前列腺癌超声造影声像图特征主要有前列腺外腺局灶性异常增强，以及内外腺分界不清。结论超声造影诊断前列腺癌的阳性预测值较高，对引导穿刺活检有一定的指导意义。
목적：탐토경직장전렬선초성조영재전렬선암활검중적림상응용개치。방법선택73례혈청전렬선특이성항원（PSA）≥4 ng/mL，차직장지검양성혹경직장초성발현가의병조적환자행초성조영검사，수후행초성조영이상증강구파향천자+6점상규천자，대초성조영미견이상자행상규6점천자。이병리결과위대조，분석초성조영도상특정。결과이병리위표준，초성조영진단전렬선암적령민도、특이도、준학솔、양성예측치、음성예측치분별위73.33%、93.02%、84.93%、88.00%、83.33%。전렬선암초성조영성상도특정주요유전렬선외선국조성이상증강，이급내외선분계불청。결론초성조영진단전렬선암적양성예측치교고，대인도천자활검유일정적지도의의。
Objective To explore the clinical application value of contrast-enhanced ultrasound (CEUS) in the diagnosis of prostate cancer and guiding prostate puncture biopsy. Methods A total of 73 patients with serum prostate specific antigen (PSA)≥4 ng/mL and abnormal findings of digital rectal examination or suspected lesions examined with transrectal ultrasonography (TRUS) underwent CEUS. Then transracial ultrasound-guided prostate biopsy (TRUPB) was performed at the suspicious region and conventional puncture was performed at+6 o’clock position simultaneously. The patients with no abnormal CEUS findings received conventional puncture at 6 o’clock position. The CEUS features were analyzed and compared with the pathological results. Results The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of CEUS was 73.33%, 93.02%, 84.93%, 88.00% and 83.33%, respectively. The CEUS features of prostate cancer mainly included focal abnormal contrast enhancement and no clear boundary between inner and outer glands. Conclusion CEUS has a high positive predictive value in the diagnosis of prostate cancer, and is of significance in guiding prostate puncture biopsy.