CAJ | 학술논문

目的：研究2,4-二氯苄醇的消毒性能。方法采用载体定量杀菌实验和文献调研相结合的方式，研究2,4-二氯苄醇有效杀菌浓度和安全性。结果2,4-二氯苄醇浓度在0.2%~0.3%之间，对大肠杆菌、白色念珠菌、金黄色葡萄球菌作用1 min，菌落杀灭对数值均＞3.00。经文献检索，大鼠经口LD50为3000 mg/kg，亚急性毒性结果为阴性；1%的2,4-二氯苄醇对皮肤无刺激。结论2,4-二氯苄醇可用于皮肤消毒和卫生手消毒，具有良好的安全性。
목적：연구2,4-이록변순적소독성능。방법채용재체정량살균실험화문헌조연상결합적방식，연구2,4-이록변순유효살균농도화안전성。결과2,4-이록변순농도재0.2%~0.3%지간，대대장간균、백색념주균、금황색포도구균작용1 min，균락살멸대수치균＞3.00。경문헌검색，대서경구LD50위3000 mg/kg，아급성독성결과위음성；1%적2,4-이록변순대피부무자격。결론2,4-이록변순가용우피부소독화위생수소독，구유량호적안전성。
objective To research the disinfection efficacy of 2, 4-dichlorobenzyl alcohol. Methods The effective bactericidal concentration and safety of 2,4-dichlorobenzyl alcohol were evaluated by quantitative germicidal test and literature research. Results The average killing log value of 0.2%-0.3%2,4-dichlorobenzyl alcohol to Staphylococcus aureus, Escherichia coli, Candida albicans for 1 min were all larger than 3.00. As already reported, the oral LD50 for rats was 3000 mg/kg, the subacute toxicity test showed negative, and 1%of 2,4-dichlorobenzyl alcohol had no stimulation on the skin. Conclusion 2,4-dichlorobenzyl alcohol is an effective and safe disinfectant, without toxicity and skin irritation, which is suitable for the disinfection application on skin and hand.