CAJ | 학술논문

目的：探讨参附注射液发生药品不良反应（ADR）的规律和原因，为临床合理用药提供参考。方法将我院2000年5月～2012年12月临床各科室上报的60例参附注射液ADR按患者性别，年龄，用法用量，原患疾病，ADR发生时间，ADR累及系统-器官及主要临床表现等进行统计分析。结果参附注射液ADR以皮肤损害为主，消化系统次之，有迟发反应的特性，但未发现死亡报告。结论参附注射液的ADR与剂量和年龄有关，关注迟发型不良反应的发生，临床应加强参附注射液的不良反应监测。
목적：탐토삼부주사액발생약품불량반응（ADR）적규률화원인，위림상합리용약제공삼고。방법장아원2000년5월～2012년12월림상각과실상보적60례삼부주사액ADR안환자성별，년령，용법용량，원환질병，ADR발생시간，ADR루급계통-기관급주요림상표현등진행통계분석。결과삼부주사액ADR이피부손해위주，소화계통차지，유지발반응적특성，단미발현사망보고。결론삼부주사액적ADR여제량화년령유관，관주지발형불량반응적발생，림상응가강삼부주사액적불량반응감측。
Objective To explore the regularity and causes of ADR caused by Shenfu injection in our hospital, and provide a reference for the clinical use of drugs. Methods We analyzed 60 cases of Shenfu injection ADR reported by clinical departments of our hospital from May 2000 to December 2012 in terms of sex, age, usage and dosage, the original illness, ADR time of occurrence, ADR involving system-organs and major clinical manifestations. Results The main ADR of Shenfu injection was skin lesion, followed by digestive system, and has the characteristics of delayed reaction, but no death case was found. Conclusion The ADR of Shenfu injection was related with dose and age, the delayed reaction was worthy to observe and the ADR monitoring of Shenfu injection should be strengthened.