CAJ | 학술논문

目的：探讨超声引导下注射不同剂量凝血酶治疗血管介入诊疗术后股动脉假性动脉瘤的疗效和不良反应。方法将48例于襄阳市中心医院行血管介入术后形成股动脉假性动脉瘤的患者随机分为两组，观察组注射凝血酶液为100 U/ml，对照组注射凝血酶液为500 U/ml，在超声引导下于瘤腔内注射凝血酶。结果观察组和对照组患者特征、注射凝血酶次数及操作时间差异无统计学意义，观察组有1例术后1天复发，对照组全部成功。对照组有2例发生股浅动脉栓塞，1例术后1周内有低热，观察组无不良反应发生。结论在超声引导下注射凝血酶治疗血管介入诊疗术后股动脉假性动脉瘤，小剂量注射凝血酶同样有效，而且可能降低注射凝血酶的风险。
목적：탐토초성인도하주사불동제량응혈매치료혈관개입진료술후고동맥가성동맥류적료효화불량반응。방법장48례우양양시중심의원행혈관개입술후형성고동맥가성동맥류적환자수궤분위량조，관찰조주사응혈매액위100 U/ml，대조조주사응혈매액위500 U/ml，재초성인도하우류강내주사응혈매。결과관찰조화대조조환자특정、주사응혈매차수급조작시간차이무통계학의의，관찰조유1례술후1천복발，대조조전부성공。대조조유2례발생고천동맥전새，1례술후1주내유저열，관찰조무불량반응발생。결론재초성인도하주사응혈매치료혈관개입진료술후고동맥가성동맥류，소제량주사응혈매동양유효，이차가능강저주사응혈매적풍험。
Objective To investigate the efifcacy and adverse effect of ultrasound-guided injection of different dosage of thrombin in the treatment of femoral artery pseudoaneurysm formed after vascular intervention. Methods 48 cases of femoral artery pseudoaneurysm after vascular interventional operation in our hospital were randomly divided into two groups according to the dosage thrombin given.Under ultrasound guidance, patients in the observation group (n=24) received injection thrombin 100U/ml while patients in the control group received injection of thrombin 500U/ml.All the operational procedures were identical between the 2 groups. Results No statistical differences were found in clinical characteristics, total number injection needed and operation time between two groups.Recurrence pseudoaneurysm was noted in 1 cases in the observation group. 2 cases of superifcial femoral arteries thrombin and 1 case of fever were recorded in control group. There was no difference in adverse event rates between the 2 group. Conclusions Ultrasound-guided injection with low dose thrombin in the treatment of post interventional femoral artery pseudoaneurysm is equally effective as higher dose.