CAJ | 학술논문

中危（次大面积）急性肺栓塞患者是否需要溶栓治疗已经争论了很多年。中危肺栓塞患者具有较高的死亡风险。因此，有人建议给予中危肺栓塞患者溶栓治疗，溶栓治疗可以更快地溶解血栓，从而降低中危肺栓塞患者的病死率。但也有研究表明，与单纯抗凝治疗比较，溶栓治疗不能进一步降低中危急性肺栓塞患者的病死率和复发率，且并发出血率较高。该文就中危急性肺栓塞溶栓治疗的有效性及安全性作一综述。
중위（차대면적）급성폐전새환자시부수요용전치료이경쟁론료흔다년。중위폐전새환자구유교고적사망풍험。인차，유인건의급여중위폐전새환자용전치료，용전치료가이경쾌지용해혈전，종이강저중위폐전새환자적병사솔。단야유연구표명，여단순항응치료비교，용전치료불능진일보강저중위급성폐전새환자적병사솔화복발솔，차병발출혈솔교고。해문취중위급성폐전새용전치료적유효성급안전성작일종술。
The necessity of thrombolysis for the patients with acute moderate risk pulmonary embolism has been debated for many years. The patients with moderate risk pulmonary embolism have a higher mortality risk for death. It has been suggested that thrombolytic treatment,which dissolves blood clots more rapidly,may reduce the mortality in those patients. But some studies show that thrombolysis cannot reduce the mortality or recurrence of acute moderate risk pulmonary embolism compared with anticoagulation. Furthermore,thromboly-sis increases the risk of bleeding. This article reviews the efficacy and safety of thrombolysis for the patients with acute moderate risk pulmonary embolism.