实用肝脏病杂志
實用肝髒病雜誌
실용간장병잡지
JOURNAL OF CLINICAL HEPATOLOGY
2014年
3期
291-294
,共4页
卢加发%潘勤%陈光榆%沈峰%章瑞南%朱婵艳%陈一铭%张舒宜%吴佳瑜%范建高
盧加髮%潘勤%陳光榆%瀋峰%章瑞南%硃嬋豔%陳一銘%張舒宜%吳佳瑜%範建高
로가발%반근%진광유%침봉%장서남%주선염%진일명%장서의%오가유%범건고
肝脏脂肪变%瞬时弹性记录仪%受控衰减参数%回归方程
肝髒脂肪變%瞬時彈性記錄儀%受控衰減參數%迴歸方程
간장지방변%순시탄성기록의%수공쇠감삼수%회귀방정
Liver steatosis%FibroScan%Controlled attenuation parameter%Regression equation
目的：探讨影响普通人群肝脏受控衰减参数的相关因素。方法使用 FibroScan○R-520诊断仪检测208例健康体检者肝脏受控衰减参数（CAP 值），同时获取受试者的主要生化指标和性别、年龄、体质量指数、腰高比、腰臀比，对其进行多元线性回归分析和偏最小二乘回归分析，建立回归方程。结果多元线性回归分析显示， CAP 值与体质量指数、腰臀比和年龄呈显著性相关，其标准回归系数分别为：体质量指数，β=0.2538，P=0.0007；腰臀比，β=0.1781，P=0.0158；年龄，β=0.1935，P=0.0022；通过多元回归分析和偏最小二乘回归建立的模型分别为：CAP=-137.70+9.40×甘油三脂+5.40×体质量指数+176.34×腰臀比+1.60×年龄，改良的 CAP=-135.23+11.57×甘油三脂+4.82×体质量指数+212.81×腰臀比+1.12×年龄。结论普通人群 CAP 正常值范围受体质量指数、腰臀比和年龄的影响，改良的回归模型能更好地反映肝脏 CAP 值。
目的：探討影響普通人群肝髒受控衰減參數的相關因素。方法使用 FibroScan○R-520診斷儀檢測208例健康體檢者肝髒受控衰減參數（CAP 值），同時穫取受試者的主要生化指標和性彆、年齡、體質量指數、腰高比、腰臀比，對其進行多元線性迴歸分析和偏最小二乘迴歸分析，建立迴歸方程。結果多元線性迴歸分析顯示， CAP 值與體質量指數、腰臀比和年齡呈顯著性相關，其標準迴歸繫數分彆為：體質量指數，β=0.2538，P=0.0007；腰臀比，β=0.1781，P=0.0158；年齡，β=0.1935，P=0.0022；通過多元迴歸分析和偏最小二乘迴歸建立的模型分彆為：CAP=-137.70+9.40×甘油三脂+5.40×體質量指數+176.34×腰臀比+1.60×年齡，改良的 CAP=-135.23+11.57×甘油三脂+4.82×體質量指數+212.81×腰臀比+1.12×年齡。結論普通人群 CAP 正常值範圍受體質量指數、腰臀比和年齡的影響，改良的迴歸模型能更好地反映肝髒 CAP 值。
목적：탐토영향보통인군간장수공쇠감삼수적상관인소。방법사용 FibroScan○R-520진단의검측208례건강체검자간장수공쇠감삼수（CAP 치），동시획취수시자적주요생화지표화성별、년령、체질량지수、요고비、요둔비，대기진행다원선성회귀분석화편최소이승회귀분석，건립회귀방정。결과다원선성회귀분석현시， CAP 치여체질량지수、요둔비화년령정현저성상관，기표준회귀계수분별위：체질량지수，β=0.2538，P=0.0007；요둔비，β=0.1781，P=0.0158；년령，β=0.1935，P=0.0022；통과다원회귀분석화편최소이승회귀건립적모형분별위：CAP=-137.70+9.40×감유삼지+5.40×체질량지수+176.34×요둔비+1.60×년령，개량적 CAP=-135.23+11.57×감유삼지+4.82×체질량지수+212.81×요둔비+1.12×년령。결론보통인군 CAP 정상치범위수체질량지수、요둔비화년령적영향，개량적회귀모형능경호지반영간장 CAP 치。
Objective To explore the related factors of controlled attenuation parameter (CAP) of liver ob-tained by FibroScan examination in healthy individuals. Methods The CAP was obtained by FibroScan in 208 healthy persons,and the main biochemical indexes,gender,age,body mass index (BMI),waist-hip ratio (WHR) and waist-height ratio were collected at the same time,and the relationship between CAP value and these common indi-cators was analyzed. Results Multiple linear regression analysis showed that CAP value was significantly correlated with BMI,WHR and age (for BMI,β=0.280,P=0.0002;for WHR,β=0.206,P=0.0059;for age,β=0.192,P=0.0022);And the regression equation established after multiple linear regression analysis and partial least squares regression were CAP=-137.70+9.40*TG+5.40*BMI+176.34*WHR+1.60*age and the adjusted CAP=-92.11+10.67*TG- 10.25*HDL+4.45*BMI+196.25*WHR+1.03*age. Conclusions The range of CAP value is affected by BMI,WHR,and age in the general population,the adjusted regression equation is more better to predict the CAP value of the liver.
