广西医学
廣西醫學
엄서의학
GUANGXI MEDICAL JOURNAL
2014年
3期
335-337
,共3页
脑梗死%幽门螺杆菌%血脂%超敏C-反应蛋白
腦梗死%幽門螺桿菌%血脂%超敏C-反應蛋白
뇌경사%유문라간균%혈지%초민C-반응단백
Cerebral infarction%Helicobacter pylori%Blood lipid%High-sensitivity C-reactive protein
目的:观察脑梗死患者幽门螺杆菌(HP)感染情况,探讨其对超敏C反应蛋白(hs-CRP)、血脂代谢的影响。方法应用酶联免疫吸附分析法检测54例脑梗死患者(观察组)及50例体检健康者(对照组)血清HP抗体(HP-IgG),同时检测观察组患者血清甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)及载脂蛋白A、B(ApoA、ApoB)及hs-CRP水平。结果观察组HP-IgG阳性率为66.7%(36/54),明显高于对照组的44.0%(22/50)(P<0.05);观察组中HP-IgG阳性患者血清TG、TC、LDL-C、ApoA、ApoB及hs-CRP水平均明显高于HP-IgG阴性患者(P<0.05),而HDL-C明显低于HP-IgG阴性患者(P<0.05)。结论 HP感染与脑梗死的发生有密切关系,且前者可能影响脑梗死患者血脂及 hs-CRP代谢。
目的:觀察腦梗死患者幽門螺桿菌(HP)感染情況,探討其對超敏C反應蛋白(hs-CRP)、血脂代謝的影響。方法應用酶聯免疫吸附分析法檢測54例腦梗死患者(觀察組)及50例體檢健康者(對照組)血清HP抗體(HP-IgG),同時檢測觀察組患者血清甘油三酯(TG)、總膽固醇(TC)、高密度脂蛋白膽固醇(HDL-C)、低密度脂蛋白膽固醇(LDL-C)及載脂蛋白A、B(ApoA、ApoB)及hs-CRP水平。結果觀察組HP-IgG暘性率為66.7%(36/54),明顯高于對照組的44.0%(22/50)(P<0.05);觀察組中HP-IgG暘性患者血清TG、TC、LDL-C、ApoA、ApoB及hs-CRP水平均明顯高于HP-IgG陰性患者(P<0.05),而HDL-C明顯低于HP-IgG陰性患者(P<0.05)。結論 HP感染與腦梗死的髮生有密切關繫,且前者可能影響腦梗死患者血脂及 hs-CRP代謝。
목적:관찰뇌경사환자유문라간균(HP)감염정황,탐토기대초민C반응단백(hs-CRP)、혈지대사적영향。방법응용매련면역흡부분석법검측54례뇌경사환자(관찰조)급50례체검건강자(대조조)혈청HP항체(HP-IgG),동시검측관찰조환자혈청감유삼지(TG)、총담고순(TC)、고밀도지단백담고순(HDL-C)、저밀도지단백담고순(LDL-C)급재지단백A、B(ApoA、ApoB)급hs-CRP수평。결과관찰조HP-IgG양성솔위66.7%(36/54),명현고우대조조적44.0%(22/50)(P<0.05);관찰조중HP-IgG양성환자혈청TG、TC、LDL-C、ApoA、ApoB급hs-CRP수평균명현고우HP-IgG음성환자(P<0.05),이HDL-C명현저우HP-IgG음성환자(P<0.05)。결론 HP감염여뇌경사적발생유밀절관계,차전자가능영향뇌경사환자혈지급 hs-CRP대사。
Objective To observe the situation of helicobacter pylori ( HP) infection in patients with cerebral infarction,and to investigate its effect on high-sensitivity C-reactive protein ( hs-CRP) and blood lipid metabolism. Methods Enzyme linked immunosorbentassay ( ELISA) was used to test the serum HP antibody Ig-G( HP-IgG) in 54 cases of cerebral infarction(observation goup) and 50 normal volunteers(control group).At the same time,the serum levels of triglyceride(TG),total cholesterol(TC),high density lipoprotein-cholesterol(HDL-C),low density lipopro-tein-cholesterol(LDL-C),apolipoprotein A(ApoA),apolipoprotein B(ApoB) and hs-CRP in the observation group were detected.Results The positive rate of serum HP-IgG in the observation group was 66.7%(36/54),which was significantly higher than that[44.0%(22/50)]of control group(P<0.05).The serum levels of TG,TC,LDL-C, ApoA,ApoB and hs-CRP in HP-IgG ( +) cases were significantly higher than those in HP-IgG ( -) cases in the observation group(P<0.05),and the serum level of HDL-C in Hp-IgG(+) cases was significantly lower than that in HP-IgG(-) cases(P<0.05).Conclusion HP infection closely associates with cerebral infarction ,it may influence the levels of blood lipid and hs-CRP in patients with cerebral infarction .