CAJ | 학술논문

目的：探讨注射HCG次日，血清HCG/LH比值的高低对获卵率的影响，并确定合适的临床参数。方法通过对本中心194例体外受精-胚胎移植超促排卵患者的数据分析，比较了HCG次日HCG/LH比值水平，并取比值1.0为界分为两组，分别比较两组获卵率和可利用胚胎率。结果通过对两组数据的分析，从总体的临床结局上看，两者无明显差异，但是从获得的卵子数上来讲,1组（HCG/LH≤1.0）获卵率要高于2组（HCG/LH＞1.0）（84.49%vs71.35%），可利用胚胎率分别为84.00%和71.30%。两者有明显的统计学差异。结论在促排卵周期中，HCG/LH水平相对越低，也就是说，LH水平较高时，所获得的卵子数是较高的，这也完全符合临床，虽然我们的临床结局没有差异，但是相对来讲，获卵率的提高，对临床妊娠率也是一种帮助。
목적：탐토주사HCG차일，혈청HCG/LH비치적고저대획란솔적영향，병학정합괄적림상삼수。방법통과대본중심194례체외수정-배태이식초촉배란환자적수거분석，비교료HCG차일HCG/LH비치수평，병취비치1.0위계분위량조，분별비교량조획란솔화가이용배태솔。결과통과대량조수거적분석，종총체적림상결국상간，량자무명현차이，단시종획득적란자수상래강,1조（HCG/LH≤1.0）획란솔요고우2조（HCG/LH＞1.0）（84.49%vs71.35%），가이용배태솔분별위84.00%화71.30%。량자유명현적통계학차이。결론재촉배란주기중，HCG/LH수평상대월저，야취시설，LH수평교고시，소획득적란자수시교고적，저야완전부합림상，수연아문적림상결국몰유차이，단시상대래강，획란솔적제고，대림상임신솔야시일충방조。
Objective To determine the effect of HCG/LH on occytes and clinical outcomes. Methods Patients in an in vitro fertilization-embryo transfer (IVF-ET) programme were treated with controlled ovarian hyperstimulation(COH).The HCG and LH level were detected after 24 hours.Then oocyte rate and available embryo for IVF-ET were analyzed between two HCG/LH ratio groups. Results The result of clinical outcomes has no statistical significance. However significant difference were noted for the number of oocytes(84.49% vs 71.35%) as well as available embryos rate(84.00% vs 71.30%) between the two groups with HCG/LH ratio ≤ 1.0 and HCG/LH> 1.0. Conclusion In the process of ovulation induction,with lower level of HCG/LH ratio or in other words with relative higher LH level the number of embryos would be achieved. Although has no statistical significance for clinical outcomes,higher vailable embryo rate would be helpful for pregnancy rate in IVF-ET.