中国医药导刊
中國醫藥導刊
중국의약도간
CHINESE JOURNAL OF MEDICAL GUIDE
2014年
4期
683-684
,共2页
晚期胃癌%复方苦参注射液%化疗
晚期胃癌%複方苦參註射液%化療
만기위암%복방고삼주사액%화료
Compound matrine injection%Advanced gastric cancer%Chemotherapy
目的：探讨复方苦参注射液配合化疗在晚期胃癌治疗中的效果观察。方法：选取2010年1月至2013年1月间于我院诊治的晚期胃癌患者86例，按其就诊顺序进行编号并随机分为对照组(43例)和观察组(43例)，对照组患者进行单纯化疗治疗，观察组患者进行复方苦参注射液配合化疗治疗，观察两组患者各临床指标，并进行统计对比分析。结果：观察组患者治疗有效率51.16%明显高于对照组41.86%，组间差异具有统计学意义(P<0.05)；观察组疼痛评分(4.01±3.15)明显低于对照组(6.83±3.28)，且其胃肠道反应发生率39.53%、骨髓抑制发生率46.51%均明显低于对照组患者相应指标69.77%、60.47%，组间差异均具有统计学意义(P<0.05)；观察组患者行为改善率58.14%、体重变化阳性率30.23%均明显高于对照组患者相应指标44.19%、13.95%，组间差异具有统计学意义(P<0.05)。结论：在晚期胃癌治疗中，复方苦参注射液配合化疗治疗能够提高近期临床疗效，缓解患者癌性疼痛，减少毒副反应发生，提高患者生活质量，值得推广。
目的：探討複方苦參註射液配閤化療在晚期胃癌治療中的效果觀察。方法：選取2010年1月至2013年1月間于我院診治的晚期胃癌患者86例，按其就診順序進行編號併隨機分為對照組(43例)和觀察組(43例)，對照組患者進行單純化療治療，觀察組患者進行複方苦參註射液配閤化療治療，觀察兩組患者各臨床指標，併進行統計對比分析。結果：觀察組患者治療有效率51.16%明顯高于對照組41.86%，組間差異具有統計學意義(P<0.05)；觀察組疼痛評分(4.01±3.15)明顯低于對照組(6.83±3.28)，且其胃腸道反應髮生率39.53%、骨髓抑製髮生率46.51%均明顯低于對照組患者相應指標69.77%、60.47%，組間差異均具有統計學意義(P<0.05)；觀察組患者行為改善率58.14%、體重變化暘性率30.23%均明顯高于對照組患者相應指標44.19%、13.95%，組間差異具有統計學意義(P<0.05)。結論：在晚期胃癌治療中，複方苦參註射液配閤化療治療能夠提高近期臨床療效，緩解患者癌性疼痛，減少毒副反應髮生，提高患者生活質量，值得推廣。
목적：탐토복방고삼주사액배합화료재만기위암치료중적효과관찰。방법：선취2010년1월지2013년1월간우아원진치적만기위암환자86례，안기취진순서진행편호병수궤분위대조조(43례)화관찰조(43례)，대조조환자진행단순화료치료，관찰조환자진행복방고삼주사액배합화료치료，관찰량조환자각림상지표，병진행통계대비분석。결과：관찰조환자치료유효솔51.16%명현고우대조조41.86%，조간차이구유통계학의의(P<0.05)；관찰조동통평분(4.01±3.15)명현저우대조조(6.83±3.28)，차기위장도반응발생솔39.53%、골수억제발생솔46.51%균명현저우대조조환자상응지표69.77%、60.47%，조간차이균구유통계학의의(P<0.05)；관찰조환자행위개선솔58.14%、체중변화양성솔30.23%균명현고우대조조환자상응지표44.19%、13.95%，조간차이구유통계학의의(P<0.05)。결론：재만기위암치료중，복방고삼주사액배합화료치료능구제고근기림상료효，완해환자암성동통，감소독부반응발생，제고환자생활질량，치득추엄。
Objective:To investigate matrine injection combined with chemotherapy in the treatment of advanced gastric cancer effects observed. Methods:The 86 patients with advanced gastric cancer in our hospital from January 2010 to January 2013, its treatment are numbered sequentially and randomly divided into control group (43 cases) and observation group (43 cases) and control group patients with chemotherapy treatment, the observation group patients matrine injection combined with chemotherapy, the clinical parameters were observed, and statistically analyzed. Results:The patients have significantly higher efficiency 51.16%41.86%difference between the groups was statistically significant (P<0.05);observation group pain score (4.01±3.15) was significantly lower than the control group (6.83±3.28) , and the incidence of gastrointestinal reactions 39.53%, 46.51%incidence of bone marrow suppression were significantly lower than the control group of patients corresponding index 69.77%,60.47%, differences between groups were statistically significant (P<0.05);observation group were behavioral improvement rate 58.14%, the positive rate of 30.23%weight change were significantly higher in patients with corresponding index 44.19%,13.95%, a statistically significant difference between the groups (P<0.05).Conclusion:In the treatment of advanced gastric cancer, matrine injection combined with chemotherapy can improve the short-term clinical efficacy in patients with cancer pain relief and reduce toxicity occur, improve patient quality of life, worthy of promotion.
