国际眼科杂志
國際眼科雜誌
국제안과잡지
INTERNATIONAL JOURNAL OF OPHTHALMOLOGY
2014年
5期
872-874
,共3页
张进%薛国民%张巧云%曹晔
張進%薛國民%張巧雲%曹曄
장진%설국민%장교운%조엽
中心性浆液性脉络膜视网膜病变%低能量激光%正相关性%荧光造影
中心性漿液性脈絡膜視網膜病變%低能量激光%正相關性%熒光造影
중심성장액성맥락막시망막병변%저능량격광%정상관성%형광조영
central serous chorioretinopathy%low energy laser%positive correlation%fluorescence angiography
目的：分析低能量视网膜激光光凝术治疗中心性浆液性脉络膜视网膜病变( central serous chorioretinopathy, CSC )的临床效果以及视力同渗漏位置的相关性。<br> 方法：采用低能量激光治疗渗漏点在黄斑旁中心凹外的53例中浆患者行激光封闭为治疗组。常规药物治疗的33例为对照组。对比观察两组患者治疗前后自觉症状、眼底、眼底荧光血管造影( fundus fluorescein angiography, FFA)的改变,眼底光学相干断层扫描( optical coherence tomography,OCT)检查,视力提高程度,以及治愈率、复发率。对全部126例患者的视力同渗漏位置进行相关性分析。<br> 结果：治愈率比较：治疗组术后4 wk治愈率为92.5%,对照组在用药后4 wk治愈率为30.3%。两组相比,有显著性差异(P<0.01),治疗组和对照组在治疗后2,4wk；3,6 mo均存在显著性差异( P<0.01)。对照组复发率为12.1%,治疗组复发率为11.3%。两组相比,无显著差异性(P>0.05)。非参数相关分析法对视力与荧光渗漏点位置之间的关系进行比较,其相关系数 r=0.216, P =0.0001,两者存在着线性正相关关系。<br> 结论：低能量激光对渗漏点在黄斑旁中心凹外的患者早期进行激光治疗,可以缩短病程,提高视力和临床治愈率,提高视觉质量,但不能降低复发率。视力与渗漏位置呈正相关性,对判断预后及治疗有临床指导作用。
目的：分析低能量視網膜激光光凝術治療中心性漿液性脈絡膜視網膜病變( central serous chorioretinopathy, CSC )的臨床效果以及視力同滲漏位置的相關性。<br> 方法：採用低能量激光治療滲漏點在黃斑徬中心凹外的53例中漿患者行激光封閉為治療組。常規藥物治療的33例為對照組。對比觀察兩組患者治療前後自覺癥狀、眼底、眼底熒光血管造影( fundus fluorescein angiography, FFA)的改變,眼底光學相榦斷層掃描( optical coherence tomography,OCT)檢查,視力提高程度,以及治愈率、複髮率。對全部126例患者的視力同滲漏位置進行相關性分析。<br> 結果：治愈率比較：治療組術後4 wk治愈率為92.5%,對照組在用藥後4 wk治愈率為30.3%。兩組相比,有顯著性差異(P<0.01),治療組和對照組在治療後2,4wk；3,6 mo均存在顯著性差異( P<0.01)。對照組複髮率為12.1%,治療組複髮率為11.3%。兩組相比,無顯著差異性(P>0.05)。非參數相關分析法對視力與熒光滲漏點位置之間的關繫進行比較,其相關繫數 r=0.216, P =0.0001,兩者存在著線性正相關關繫。<br> 結論：低能量激光對滲漏點在黃斑徬中心凹外的患者早期進行激光治療,可以縮短病程,提高視力和臨床治愈率,提高視覺質量,但不能降低複髮率。視力與滲漏位置呈正相關性,對判斷預後及治療有臨床指導作用。
목적：분석저능량시망막격광광응술치료중심성장액성맥락막시망막병변( central serous chorioretinopathy, CSC )적림상효과이급시력동삼루위치적상관성。<br> 방법：채용저능량격광치료삼루점재황반방중심요외적53례중장환자행격광봉폐위치료조。상규약물치료적33례위대조조。대비관찰량조환자치료전후자각증상、안저、안저형광혈관조영( fundus fluorescein angiography, FFA)적개변,안저광학상간단층소묘( optical coherence tomography,OCT)검사,시력제고정도,이급치유솔、복발솔。대전부126례환자적시력동삼루위치진행상관성분석。<br> 결과：치유솔비교：치료조술후4 wk치유솔위92.5%,대조조재용약후4 wk치유솔위30.3%。량조상비,유현저성차이(P<0.01),치료조화대조조재치료후2,4wk；3,6 mo균존재현저성차이( P<0.01)。대조조복발솔위12.1%,치료조복발솔위11.3%。량조상비,무현저차이성(P>0.05)。비삼수상관분석법대시력여형광삼루점위치지간적관계진행비교,기상관계수 r=0.216, P =0.0001,량자존재착선성정상관관계。<br> 결론：저능량격광대삼루점재황반방중심요외적환자조기진행격광치료,가이축단병정,제고시력화림상치유솔,제고시각질량,단불능강저복발솔。시력여삼루위치정정상관성,대판단예후급치료유림상지도작용。
AIM:To analyze the low energy laser photocoagulation under treatment of central serous chorioretinopathy ( CSC) correlation of clinical effect and visual acuity with leakage location. <br> METHODS:Using low energy laser on the leakage point in the parafoveal and 53 cases of central serous chorioretinopathy patients underwent laser closed, drug treatment group and 33 cases as control. Comparison of two groups was observed before and after treatment in patients with symptoms, ocular fundus, fundus fluorescein angiography ( FFA ) changes, fundus optical coherence tomography technology ( OCT ) examination, visual acuity improved in degree, and the relationship between the cure rate, relapse rate. All 126 cases were associated with visual leakage location analysis. <br> RESULTS:The cure rate of lasercomparison: 4 weeks after operation, the cure rate was 92. 5%. The drug therapy group at 4 weeks after treatment cure rate was 30.3%.The two groups were compared(P<0. 01), and there was significant difference. The laser group and treatment group after treatment in 2 weeks, 4 weeks, in March June, and there was significant difference ( P<0.01 ) . The medicine group the recurrence rate was 12.1%, the lasertreatment group and recurrence rate was 11. 3%. The two groups were compared, no significant difference (P>0. 05). Nonparametriccorrelation analysis method to compare the relationship between visual acuity and fluorescence leakage point location, the correlation coefficient (r=0. 216, P=0. 0001), there is a positive linear correlation between. <br> CONCLUSION: The leakage point in the parafoveal outside in early stagelaser in the treatment of low energy laser, can shorten the course of disease, improve the cure rate of visual acuity and clinical, and improve the visual quality, but can not reduce the recurrence rate. There is a positive correlation between visual acuity and leakage location, clinicalguidance for prognosis and treatment.
