目的：应用Cirrus HD OCT检测近视眼视网膜神纤维层厚度,探讨近视眼神经纤维层厚度分布特点及其与屈光度的关系。<br> 方法：将近视眼106例196眼分为低、中、高度近视组和正常对照组38例60眼,应用Cirrus HD OCT进行以视盘为中心,直径3.46 mm圆周的RNFL厚度测量,计算各组平均、各象限及各钟点RNFL厚度,各近视组分别与正常对照组对比,研究近视眼RNFL厚度与屈光度的关系。<br> 结果：各近视组平均、上方象限及下方象限RNFL厚度较正常对照组变薄,其中中度、高度近视与正常对照组相比有统计学差异( P<0.05),鼻侧象限RNFL厚度变薄,无统计学显著性差异( P>0.05),颞侧象限RNFL厚度增加,有统计学差异( P<0.05)；各近视组2：00,6：00,12：00位RNFL厚度较正常对照组变薄,有统计学差异( P<0.05),8：00,9：00,10：00位RNFL厚度较正常对照组增加,有统计学差异( P<0.05),中、高度近视1：00,5：00位厚度较正常对照组变薄,有统计学差异(P<0.05)。<br> 结论：近视眼平均、上方及下方象限、2：00,6：00,12：00位RNFL厚度较正常对照组变薄,颞侧象限、8：00,9：00,10：00位RNFL厚度较正常对照组相比明显增加,这是近视眼RNFL厚度的特点,当临床出现RNFL厚度异常时,应考虑屈光度的影响,综合评价其临床意义；近视眼7：00,8：00,10：00,11：00位RNFL厚度与正常对照组相比均未变薄,出现异常变薄时,应考虑青光眼可能。
目的：應用Cirrus HD OCT檢測近視眼視網膜神纖維層厚度,探討近視眼神經纖維層厚度分佈特點及其與屈光度的關繫。<br> 方法：將近視眼106例196眼分為低、中、高度近視組和正常對照組38例60眼,應用Cirrus HD OCT進行以視盤為中心,直徑3.46 mm圓週的RNFL厚度測量,計算各組平均、各象限及各鐘點RNFL厚度,各近視組分彆與正常對照組對比,研究近視眼RNFL厚度與屈光度的關繫。<br> 結果：各近視組平均、上方象限及下方象限RNFL厚度較正常對照組變薄,其中中度、高度近視與正常對照組相比有統計學差異( P<0.05),鼻側象限RNFL厚度變薄,無統計學顯著性差異( P>0.05),顳側象限RNFL厚度增加,有統計學差異( P<0.05)；各近視組2：00,6：00,12：00位RNFL厚度較正常對照組變薄,有統計學差異( P<0.05),8：00,9：00,10：00位RNFL厚度較正常對照組增加,有統計學差異( P<0.05),中、高度近視1：00,5：00位厚度較正常對照組變薄,有統計學差異(P<0.05)。<br> 結論：近視眼平均、上方及下方象限、2：00,6：00,12：00位RNFL厚度較正常對照組變薄,顳側象限、8：00,9：00,10：00位RNFL厚度較正常對照組相比明顯增加,這是近視眼RNFL厚度的特點,噹臨床齣現RNFL厚度異常時,應攷慮屈光度的影響,綜閤評價其臨床意義；近視眼7：00,8：00,10：00,11：00位RNFL厚度與正常對照組相比均未變薄,齣現異常變薄時,應攷慮青光眼可能。
목적：응용Cirrus HD OCT검측근시안시망막신섬유층후도,탐토근시안신경섬유층후도분포특점급기여굴광도적관계。<br> 방법：장근시안106례196안분위저、중、고도근시조화정상대조조38례60안,응용Cirrus HD OCT진행이시반위중심,직경3.46 mm원주적RNFL후도측량,계산각조평균、각상한급각종점RNFL후도,각근시조분별여정상대조조대비,연구근시안RNFL후도여굴광도적관계。<br> 결과：각근시조평균、상방상한급하방상한RNFL후도교정상대조조변박,기중중도、고도근시여정상대조조상비유통계학차이( P<0.05),비측상한RNFL후도변박,무통계학현저성차이( P>0.05),섭측상한RNFL후도증가,유통계학차이( P<0.05)；각근시조2：00,6：00,12：00위RNFL후도교정상대조조변박,유통계학차이( P<0.05),8：00,9：00,10：00위RNFL후도교정상대조조증가,유통계학차이( P<0.05),중、고도근시1：00,5：00위후도교정상대조조변박,유통계학차이(P<0.05)。<br> 결론：근시안평균、상방급하방상한、2：00,6：00,12：00위RNFL후도교정상대조조변박,섭측상한、8：00,9：00,10：00위RNFL후도교정상대조조상비명현증가,저시근시안RNFL후도적특점,당림상출현RNFL후도이상시,응고필굴광도적영향,종합평개기림상의의；근시안7：00,8：00,10：00,11：00위RNFL후도여정상대조조상비균미변박,출현이상변박시,응고필청광안가능。
AIM:To investigate the characteristics of the retinal nerve fibre layer ( RNFL ) thickness in myopia measured by Cirrus HD optical coherence tomography ( OCT ) , and the relationship between RNFL thickness and refractive diopter/axial length. <br> METHODS: Totally 106 cases ( 196 eyes ) were divided into low, moderate and high myopia group and 38 cases (60 eyes) as normal group were included in the study. Cirrus HD OCT was used to measure the RNFL thickness. Each eye was performed circular scans around the optic nerve with a circle size of 3. 46mm. The average RNFL thickness, the mean RNFL thickness in each quadrant and clock hour in each group were recorded. The difference between each myopia group and normal group and the relationship between RNFL thickness and refractive diopter was researched. <br> RESULTS: Compared to normal group, the average RNFL thickness, the mean RNFL thickness of superior and inferior were thinner in myopia groups, the difference between moderate, high myopia group and normal group were significant ( P< 0. 05 ), the nasal quadrant RNFL thickness was also thinner, but the difference was not significant ( P > 0. 05 ), the temporal quadrant RNFL thickness was thicker and the difference was significant ( P<0. 05); Compared to normal group, at 2:00, 6:00, 12:00 position, the RNFL thickness decreased significantly in each myopia group ( P<0. 05 ); at 8:00, 9:00, 10:00 position, the RNFL thickness increased significantly ( P<0.05);at 1:00, 5:00 position in moderate, high myopia group, the RNFL thickness decreased significantly ( P<0.05). <br> CONCLUSION: The average RNFL thickness and the RNFL thickness at superior quadrant, inferior quadrant, 2:00, 6:00, 12:00 position in myopia groups are thinner than normal group; the RNFL thickness at temporal quadrant, 8:00, 9:00 and 10:00 position are thicker. The result shows the characteristics of the RNFL thickness in myopia, which is of instructive significance to guide the diagnosis of disease. Effect of refractive diopter on RNFL should be concerned for a clinical diagnosis; The RNFL thickness at 7:00, 8:00, 10:00 and 11:00 position in myopia group are not thinner than normal group. If they become thinner, glaucoma should be considered.
