CAJ | 학술논문

目的：观察柔肝归魂法治疗卒中后抑郁的临床疗效。方法：采用开放式随机对照方法，将87例患者分为两组，分别用柔肝归魂法（治疗组45例）和百忧解（对照组42例）治疗4周，于治疗前后应用汉密尔顿抑郁量表（HAMD）、自拟中医证候等级评分量表评定药物疗效，并同时观察药物不良反应。结果：两组临床疗效比较差异无显著性（P>0.05）；两组治疗后HAMD积分均明显低于治疗前（P<0.05），两组间比较差异无显著性（P>0.05）；在改善中医证候方面，治疗组优于对照组（P<0.05）；治疗组不良反应明显低于对照组。结论：柔肝归魂法对卒中后抑郁的临床疗效与百忧解相当；缓解躯体症状优于百忧解；无明显不良反应。
목적：관찰유간귀혼법치료졸중후억욱적림상료효。방법：채용개방식수궤대조방법，장87례환자분위량조，분별용유간귀혼법（치료조45례）화백우해（대조조42례）치료4주，우치료전후응용한밀이돈억욱량표（HAMD）、자의중의증후등급평분량표평정약물료효，병동시관찰약물불량반응。결과：량조림상료효비교차이무현저성（P>0.05）；량조치료후HAMD적분균명현저우치료전（P<0.05），량조간비교차이무현저성（P>0.05）；재개선중의증후방면，치료조우우대조조（P<0.05）；치료조불량반응명현저우대조조。결론：유간귀혼법대졸중후억욱적림상료효여백우해상당；완해구체증상우우백우해；무명현불량반응。
Objective:To observe the efficacy of Rougan Guihun therapy on treating post-stroke depression (PSD). Methods:Using open randomized controlled method, 87 patients were divided into two groups, using Rougan Guihun therapy (treated group 45 cases) and prozac (control group 42 cases), 4 weeks treatment in the application before and after treatment to Hamilton depressive scale (HAMD), the TCM syndrome grade rating scale to assess efficacy, and at the same time observe the adverse drug reactions. Results: There was no significant difference compared two groups of clinical curative effect (P>0.05). Two groups of HAMD score after treatment were significantly lower than before treatment (P<0.05), there was no significant difference is compared between two groups (P>0.05). In terms of improving syndromes, the treated group is better than that of control group (P<0.05). Adverse reactions of treated group were obviously lower than the control group. Conclusion: Rougan Guihun therapy has the better clinical curative effect on treating PSD than Prozac. Alleviate symptoms of body is better than that of Prozac, no obvious adverse reactions.