化工进展
化工進展
화공진전
CHEMICAL INDUSTRY AND ENGINEERING PROGRESS
2014年
5期
1259-1264
,共6页
农韦健%陈小鹏%梁杰珍%王琳琳%黄科林%史磊%吴睿%李克贤
農韋健%陳小鵬%樑傑珍%王琳琳%黃科林%史磊%吳睿%李剋賢
농위건%진소붕%량걸진%왕림림%황과림%사뢰%오예%리극현
枞酸%单离%生物活性
樅痠%單離%生物活性
종산%단리%생물활성
abietic acid%isolation%bioactivity
枞酸是从天然可再生资源松香中分离得到的产品,由于松香是包含13种树脂酸的混合物,而且这些树脂酸多为同分异构体,导致其物理性质相近,使得枞酸单离非常困难,很多情况下是以混合物的形式应用于各种工业领域中,用途受到了一定的限制。本文介绍了枞酸的几种主要单离方法,分析了各种单离方法的优缺点,认为有机胺盐结晶法是枞酸工业生产最可行的方法。此外,本文还介绍了枞酸在合成生物活性物质方面的应用以及在医药、农药、精细化学品等领域的应用研究进展,最后,指出将松香所含的多种树脂酸逐一分离提纯,并以之作为原料,合成一系列具有生物活性的物质和药物,是未来枞酸综合开发利用的重点。
樅痠是從天然可再生資源鬆香中分離得到的產品,由于鬆香是包含13種樹脂痠的混閤物,而且這些樹脂痠多為同分異構體,導緻其物理性質相近,使得樅痠單離非常睏難,很多情況下是以混閤物的形式應用于各種工業領域中,用途受到瞭一定的限製。本文介紹瞭樅痠的幾種主要單離方法,分析瞭各種單離方法的優缺點,認為有機胺鹽結晶法是樅痠工業生產最可行的方法。此外,本文還介紹瞭樅痠在閤成生物活性物質方麵的應用以及在醫藥、農藥、精細化學品等領域的應用研究進展,最後,指齣將鬆香所含的多種樹脂痠逐一分離提純,併以之作為原料,閤成一繫列具有生物活性的物質和藥物,是未來樅痠綜閤開髮利用的重點。
종산시종천연가재생자원송향중분리득도적산품,유우송향시포함13충수지산적혼합물,이차저사수지산다위동분이구체,도치기물이성질상근,사득종산단리비상곤난,흔다정황하시이혼합물적형식응용우각충공업영역중,용도수도료일정적한제。본문개소료종산적궤충주요단리방법,분석료각충단리방법적우결점,인위유궤알염결정법시종산공업생산최가행적방법。차외,본문환개소료종산재합성생물활성물질방면적응용이급재의약、농약、정세화학품등영역적응용연구진전,최후,지출장송향소함적다충수지산축일분리제순,병이지작위원료,합성일계렬구유생물활성적물질화약물,시미래종산종합개발이용적중점。
Abietic acid is a product isolated from natural renewable resource rosin. Because rosin is a mixture containing thirteen kinds of resin acid and most of these resin acids are isomers,which results in a similarity of their physical properties,it makes the isolation of abietic acid from rosin a difficult problem. In most cases,abietic acid is used as a mixture form in many industrial fields,and the applications are restricted to some extent. Several major isolation methods of abietic acid are introduced,and the advantages and disadvantages of each method are analyzed. Organic amine salt crystallization is the most feasible method for isolation of abietic acid. Furthermore,the application of abietic acid in synthesizing bioactive substances and the usage of abietic acid in medicine,pesticide and fine chemicals are introduced. Isolating every resin acid from rosin and using them as raw materials to synthesize a series substances and drugs with bioactivity are the emphasis of comprehensive development and utilization of abietic acid in the future.