中华实验和临床病毒学杂志
中華實驗和臨床病毒學雜誌
중화실험화림상병독학잡지
CHINESE JOURNAL OF EXPERIMENTAL AND CLINICAL VIROLOGY
2012年
6期
467-469
,共3页
糖尿病,非胰岛素依赖型%糖尿病神经病变%糖尿病视网膜病变
糖尿病,非胰島素依賴型%糖尿病神經病變%糖尿病視網膜病變
당뇨병,비이도소의뢰형%당뇨병신경병변%당뇨병시망막병변
Diabetes mellitus,non-insulin-dependent%Diabetic neuropathies%Diabetic retinopathy
目的 探讨糖尿病周围神经病变(DPN)的相关危险因素及DPN与糖尿病视网膜病变(DR)的关系.方法 回顾性分析200例2型糖尿病(T2DM)住院患者的病史资料,根据是否合并DPN,分为DPN组(n=136)及非DPN组(NDPN组,n=64),比较两组的临床基本资料及DR发生率,采用Logistic回归分析探讨DPN的危险因素.结果 两组间比较,病程、体质指数(BMI)、糖化血红蛋白(HbA1c)、餐后2h血糖(2 hPG)、糖负荷2小时C肽(2 hC-P)、DR发生率差异均有统计学意义(P＜0.01).Logistic多因素回归分析显示,因素合并DR(P=0.023)、病程(P =0.008)、HbA1c(P=0.006)、BMI(P =0.000)及2 hC-P水平(P =0.065)差异具有统计学意义.结论 合并DR、病程、BMI、HbA1c及2 hC-P水平是DPN发生的危险因素,DPN与DR存在正相关平行关系.
目的 探討糖尿病週圍神經病變(DPN)的相關危險因素及DPN與糖尿病視網膜病變(DR)的關繫.方法 迴顧性分析200例2型糖尿病(T2DM)住院患者的病史資料,根據是否閤併DPN,分為DPN組(n=136)及非DPN組(NDPN組,n=64),比較兩組的臨床基本資料及DR髮生率,採用Logistic迴歸分析探討DPN的危險因素.結果 兩組間比較,病程、體質指數(BMI)、糖化血紅蛋白(HbA1c)、餐後2h血糖(2 hPG)、糖負荷2小時C肽(2 hC-P)、DR髮生率差異均有統計學意義(P＜0.01).Logistic多因素迴歸分析顯示,因素閤併DR(P=0.023)、病程(P =0.008)、HbA1c(P=0.006)、BMI(P =0.000)及2 hC-P水平(P =0.065)差異具有統計學意義.結論 閤併DR、病程、BMI、HbA1c及2 hC-P水平是DPN髮生的危險因素,DPN與DR存在正相關平行關繫.
목적 탐토당뇨병주위신경병변(DPN)적상관위험인소급DPN여당뇨병시망막병변(DR)적관계.방법 회고성분석200례2형당뇨병(T2DM)주원환자적병사자료,근거시부합병DPN,분위DPN조(n=136)급비DPN조(NDPN조,n=64),비교량조적림상기본자료급DR발생솔,채용Logistic회귀분석탐토DPN적위험인소.결과 량조간비교,병정、체질지수(BMI)、당화혈홍단백(HbA1c)、찬후2h혈당(2 hPG)、당부하2소시C태(2 hC-P)、DR발생솔차이균유통계학의의(P＜0.01).Logistic다인소회귀분석현시,인소합병DR(P=0.023)、병정(P =0.008)、HbA1c(P=0.006)、BMI(P =0.000)급2 hC-P수평(P =0.065)차이구유통계학의의.결론 합병DR、병정、BMI、HbA1c급2 hC-P수평시DPN발생적위험인소,DPN여DR존재정상관평행관계.
Objective To explore the risk factors of diabetic peripheral neuropathy (DPN) and the relationship between DPN and diabetic retinopathy (DR).Methods The data of the in-patients with type 2 diabetes mellitus (T2DM) were retrospectively studied.A total of 200 T2 DM patients were divided into DPN group (n =136) and non-DPN group (n =64) according to peripheral neuropathy.The basic clinical data and the incidence rate of DR were compared between two groups.Logistic regression analysis was used to study the risk factors of DPN.Results The course of disease,the level of BMI,glycosylated hemoglobin (HbA1c),2 hour postprandial blood glucose (2 hPG),2 hour glucose C peptide (2 hC-P) and the incidence rate of the DR were significantly different between two groups (P ＜ 0.01).Logistic regression analysis showed that significant differences were observed in T2 DM complicated by DR (P =0.023),the course of disease (P =0.008),the level of HbA1c (P =0.006),BMI (P =0.000) and 2 hC-P (P =0.065).Conclusion Diabetic retinopathy,the course of disease,the level of BMI,HbA1c and 2 hC-P are the risk factors for type 2 diabetic peripheral neuropathy.Diabetic peripheral neuropathy is positive correlated with diabetic retinopathy.
