中国男科学杂志
中國男科學雜誌
중국남과학잡지
CHINESE JOURNAL OF ANDROLOGY
2014年
3期
37-39
,共3页
袁亦铭%彭晓辉%王刚%崔万寿%彭靖%张志超%高冰%宋卫东%辛钟成%周利群
袁亦銘%彭曉輝%王剛%崔萬壽%彭靖%張誌超%高冰%宋衛東%辛鐘成%週利群
원역명%팽효휘%왕강%최만수%팽정%장지초%고빙%송위동%신종성%주리군
藻酸双酯钠%阴茎异常勃起
藻痠雙酯鈉%陰莖異常勃起
조산쌍지납%음경이상발기
Polysaccharide sulfate%priapism
目的：探讨静脉滴注藻酸双酯钠导致缺血性阴茎异常勃起的临床特点及其机制。方法分析北大医院男科中心2010年至2012年收治的9例静脉滴注藻酸双酯钠后出现缺血性阴茎异常勃起患者的病史、临床表现特点、实验室检查及治疗。同时检索万方医学数据库文献，分析静脉滴注藻酸双酯钠导致的缺血性阴茎异常勃起的临床特点、治疗方法。结果万方医学数据库1998年至2013年文献共报道49例静脉滴注藻酸双脂钠后发生的阴茎异常勃起病例。我院共收治9例静脉滴注藻酸双酯钠引起的缺血性阴茎异常勃起的患者，应用藻酸双酯钠24h内发病的3例，其他为应用藻酸双酯钠2~7d；9例患者血常规及凝血功能检查均无明显异常。文献中49例患者，应用藻酸双酯钠24h内发病3例，其他应用藻酸双酯钠2~20d，平均4~5d；报道血常规及凝血结果的6例，均无异常；2例报道阴茎海绵体内血液呈高凝状态。结论静脉滴注藻酸双酯钠后，可能使阴茎海绵体局部血液粘滞状态改变，出现高凝状态，导致缺血性阴茎异常勃起发生。阴茎异常勃起出现后，应及时处理，尽早使用海绵体内缩血管药物注射、海绵体抽血或阴茎头阴茎海绵体分流术等方式处理。
目的：探討靜脈滴註藻痠雙酯鈉導緻缺血性陰莖異常勃起的臨床特點及其機製。方法分析北大醫院男科中心2010年至2012年收治的9例靜脈滴註藻痠雙酯鈉後齣現缺血性陰莖異常勃起患者的病史、臨床錶現特點、實驗室檢查及治療。同時檢索萬方醫學數據庫文獻，分析靜脈滴註藻痠雙酯鈉導緻的缺血性陰莖異常勃起的臨床特點、治療方法。結果萬方醫學數據庫1998年至2013年文獻共報道49例靜脈滴註藻痠雙脂鈉後髮生的陰莖異常勃起病例。我院共收治9例靜脈滴註藻痠雙酯鈉引起的缺血性陰莖異常勃起的患者，應用藻痠雙酯鈉24h內髮病的3例，其他為應用藻痠雙酯鈉2~7d；9例患者血常規及凝血功能檢查均無明顯異常。文獻中49例患者，應用藻痠雙酯鈉24h內髮病3例，其他應用藻痠雙酯鈉2~20d，平均4~5d；報道血常規及凝血結果的6例，均無異常；2例報道陰莖海綿體內血液呈高凝狀態。結論靜脈滴註藻痠雙酯鈉後，可能使陰莖海綿體跼部血液粘滯狀態改變，齣現高凝狀態，導緻缺血性陰莖異常勃起髮生。陰莖異常勃起齣現後，應及時處理，儘早使用海綿體內縮血管藥物註射、海綿體抽血或陰莖頭陰莖海綿體分流術等方式處理。
목적：탐토정맥적주조산쌍지납도치결혈성음경이상발기적림상특점급기궤제。방법분석북대의원남과중심2010년지2012년수치적9례정맥적주조산쌍지납후출현결혈성음경이상발기환자적병사、림상표현특점、실험실검사급치료。동시검색만방의학수거고문헌，분석정맥적주조산쌍지납도치적결혈성음경이상발기적림상특점、치료방법。결과만방의학수거고1998년지2013년문헌공보도49례정맥적주조산쌍지납후발생적음경이상발기병례。아원공수치9례정맥적주조산쌍지납인기적결혈성음경이상발기적환자，응용조산쌍지납24h내발병적3례，기타위응용조산쌍지납2~7d；9례환자혈상규급응혈공능검사균무명현이상。문헌중49례환자，응용조산쌍지납24h내발병3례，기타응용조산쌍지납2~20d，평균4~5d；보도혈상규급응혈결과적6례，균무이상；2례보도음경해면체내혈액정고응상태。결론정맥적주조산쌍지납후，가능사음경해면체국부혈액점체상태개변，출현고응상태，도치결혈성음경이상발기발생。음경이상발기출현후，응급시처리，진조사용해면체내축혈관약물주사、해면체추혈혹음경두음경해면체분류술등방식처리。
Objective To investigate the clinical characteristic and mechanism of ischemic priapism induced by intravenous Polysaccharide sulfate. Methods The medical history, characteristic of clinical manifestation, results of laboratory examination and treatments of nine patients with ischemic priapism induced by intravenous polysaccharide sulfate were comparatively analyzed and summarized. The case-reports of ischemic priapism in published literature of Wangfang Med database were reviewed. Results There were 49 case reports for patients with ischemic priapism induced by intravenous polysaccharide sulfate in Wanfang Med database. For nine patients treated in our hospital, 3 patients had priapism during 24 hours after intravenous polysaccharide sulfate, the others had priapism during 2-7 days after intravenous polysaccharide sulfate, and their blood routine examination and coagulation function test results were normal. For the 49 patients from reviews, 3 patients had priapism during 24 hours after intravenous polysaccharide sulfate, the others had priapism during 2-20 days after intravenous polysaccharide sulfate and the 2 patients had hypercoagulability. Conclusion After intravenous polysaccharide sulfate, the blood state in corpus cavernosum transitted to hypercoagulability, which resulted in priapism. The treatment to priapism should be proceeded in time.
