CAJ | 학술논문

目的：观察曲伏前列腺素和卡巴胆碱对白内障超声乳化加人工晶状体植入术后24 h眼压的影响。方法2011年3月至2013年3月我科室行白内障超声乳化加人工晶状体植入术患者150例,150眼,随机分为A、B、C 3组。 A组患者在手术前1 h于结膜囊内滴入曲伏前列腺素眼液1滴,B组患者术毕关闭切口前于前房内注射卡巴胆碱0．2 mL,C组患者术毕关闭切口前于前房注射卡巴胆碱0．2 mL,手术前于结膜囊内滴入曲伏前列腺素眼液1滴。测量并比较所有患者术前12 h及术后12、24 h眼内压力。结果与单用组( A、B组)相比,术后12 h,联合用药组(C组)眼压升高幅度最小,差异有统计学意义(P<0．05)；术后24 h,联合用药组患者眼压下降幅度最大,差异有统计学意义(P<0．05)。结论曲伏前列腺素和卡巴胆碱联合用药在预防超声乳化人工晶体植入术后24 h内眼压升高起到了良好的协同作用,值得临床推广。
목적：관찰곡복전렬선소화잡파담감대백내장초성유화가인공정상체식입술후24 h안압적영향。방법2011년3월지2013년3월아과실행백내장초성유화가인공정상체식입술환자150례,150안,수궤분위A、B、C 3조。 A조환자재수술전1 h우결막낭내적입곡복전렬선소안액1적,B조환자술필관폐절구전우전방내주사잡파담감0．2 mL,C조환자술필관폐절구전우전방주사잡파담감0．2 mL,수술전우결막낭내적입곡복전렬선소안액1적。측량병비교소유환자술전12 h급술후12、24 h안내압력。결과여단용조( A、B조)상비,술후12 h,연합용약조(C조)안압승고폭도최소,차이유통계학의의(P<0．05)；술후24 h,연합용약조환자안압하강폭도최대,차이유통계학의의(P<0．05)。결론곡복전렬선소화잡파담감연합용약재예방초성유화인공정체식입술후24 h내안압승고기도료량호적협동작용,치득림상추엄。
Objective To observe the clinical effect of travoprost and carbachol on intraocular pressure ( IOP) within 24 hours after cataract surgery. Methods 150 patients with high IOP resulted in phaco-emulsification with in-traocular lens ( IOL) implantation were randomly divided into group A ( instilling one drop of travoprost eyedrops into the culdesac about 1 h before the operation,group B ( intracameral carbachol) ,and group C ( travoprost with carbachol) . The intraocular pressure was measured 12 h before operation and 12,24 h after the surgery respectively. Results IOP were higher at 12 hours postoperatively than that of the preoperation,but group C was lower than group A and group B (P<0. 05). IOP at 24 hours after surgery decreased compared with 12 hours postoperatively and group C was the low-est (P<0. 05). Conclusion The preoperative treatment of travoprost and intraoperative treatment of carbachol togeth-er can significantly prevent high IOP within 24 hours after cataract surgery,it is worthy of chiical apphication.