食品研究与开发
食品研究與開髮
식품연구여개발
FOOD RESEARCH AND CEVELOPMENT
2014年
6期
70-74,136
,共6页
张骏%王硕%张燕%何佳%林安清
張駿%王碩%張燕%何佳%林安清
장준%왕석%장연%하가%림안청
猪肉%兽药%质谱%检测
豬肉%獸藥%質譜%檢測
저육%수약%질보%검측
pork%veterinary drug%LC-MS/MS%determination
建立了可同时检测猪肉中氯丙嗪，丙酰丙嗪，氮哌酮，氟哌啶醇，氮哌醇，咔唑心安多种兽药残留的液相色谱-串联质谱（LC-MS /MS）方法，在已有的研究基础上对样品的前处理方法进行了优化和改进，检出限均为0.5μg/kg，平均加标回收率在77.2%~100.3%之间，相对标准偏差（RSD）在4.7％~10.1％之间。该方法简单快速，回收率高，重现性好，方法回收率和精密度满足残留分析规定指标。
建立瞭可同時檢測豬肉中氯丙嗪，丙酰丙嗪，氮哌酮，氟哌啶醇，氮哌醇，咔唑心安多種獸藥殘留的液相色譜-串聯質譜（LC-MS /MS）方法，在已有的研究基礎上對樣品的前處理方法進行瞭優化和改進，檢齣限均為0.5μg/kg，平均加標迴收率在77.2%~100.3%之間，相對標準偏差（RSD）在4.7％~10.1％之間。該方法簡單快速，迴收率高，重現性好，方法迴收率和精密度滿足殘留分析規定指標。
건립료가동시검측저육중록병진，병선병진，담고동，불고정순，담고순，잡서심안다충수약잔류적액상색보-천련질보（LC-MS /MS）방법，재이유적연구기출상대양품적전처리방법진행료우화화개진，검출한균위0.5μg/kg，평균가표회수솔재77.2%~100.3%지간，상대표준편차（RSD）재4.7％~10.1％지간。해방법간단쾌속，회수솔고，중현성호，방법회수솔화정밀도만족잔류분석규정지표。
A liquid chromatography-electrospray ionization tandem mass spectrometry (LC-MS/MS) method for the determination of some residues of veterinary drug (chlorpromazine, azaperone, propionylpromazine, haloperidol, azaperol and carazolol) in pork was developed. The research optimized and improved the sample pretreatment on the basis of existing study. All of the limits of detection (LODs) of these veterinary drug were 0.5μg/kg. The average recoveries of target drugs ranged from 77.2%-100.3%with relative standard deviations (RSDs) of 4.7%-10.1%. The developed method is the suitable method for the rapid quantitative and reliable determination of veterinary drug residues. The results demonstrated that the sensitivity , accuracy and precision of this method meet the requirements of residue analysis. The method is applicable to detect these residues of veterinary drug in pork.
