CAJ | 학술논문

目的：分析天津地区秋季变应性鼻炎中医证型与变应原的关系，探讨其病因病机。方法统计分析2012年1月～2013年3月在本院行变应原皮肤点刺试验的患者1711例，对其中秋季发病的355例变应性鼻炎患者进行问诊调查，记录其发病情况，进而辨证分型，统计天津地区秋季变应性鼻炎证型与各变应原皮试反应的关系。结果本组患者秋季变应性鼻炎患病率63.8%，明显高于其他季节（P＜0.05）。秋季花粉致敏者肺气虚寒型最多，其次为脾气虚弱型；屋尘螨、粉尘螨致敏者痰湿中阻型最多，其次为肺气虚寒型；真菌类致敏者肺气虚寒型最多，其次为肾阳不足型；各证型患病率差异有统计学意义（P＜0.05）；动物皮毛致敏者各证型患病率差异无统计学意义（P＞0.05）。结论变应原种类与变应性鼻炎的发病及其辨证分型具有相关性，对于辨证治疗方案的制定具有参考意义。
목적：분석천진지구추계변응성비염중의증형여변응원적관계，탐토기병인병궤。방법통계분석2012년1월～2013년3월재본원행변응원피부점자시험적환자1711례，대기중추계발병적355례변응성비염환자진행문진조사，기록기발병정황，진이변증분형，통계천진지구추계변응성비염증형여각변응원피시반응적관계。결과본조환자추계변응성비염환병솔63.8%，명현고우기타계절（P＜0.05）。추계화분치민자폐기허한형최다，기차위비기허약형；옥진만、분진만치민자담습중조형최다，기차위폐기허한형；진균류치민자폐기허한형최다，기차위신양불족형；각증형환병솔차이유통계학의의（P＜0.05）；동물피모치민자각증형환병솔차이무통계학의의（P＞0.05）。결론변응원충류여변응성비염적발병급기변증분형구유상관성，대우변증치료방안적제정구유삼고의의。
Objective To explore the association of sensitive allergens in autumn with Chinese Medicine Syndromes (CMS) among cases with allergic rhinitis (AR) in Tianjin to investigate the etiology and pathogenesis of this condition in terms of TCM.Methods There were 1711 patients suspected with AR accepted allergen skin prick test in our Hospital from Jan, 2012 to Mar, 2013, with 335 diagnosed as AR falling ill in autumn out of them. Careful inquiring was carried out in this subgroup of cases to record their overall ill history for classifying respective CMS. Then, a statistic analysis was made to investigate the association of CMS with the distribution of positive sensitive allergens for AR cases attacking in autumn.Results The morbidity of AR in autumn was 63.8%, significantly higher than that in other seasons (P<0.05). In this subgroup of cases with AR occurring in autumn, those with fall pollens as their responsible sensitive allergens showed the pattern of Lung Qi deficiency cold as the most frequently seen CMS, with Spleen Qi deficiency as the next frequent type, and ones with Dermatophagoides pteronyssinus and Dermatophagoides culinae as the responsible sensitive allergens showed the pattern of Phlegm-damp blocking center as the most frequently seen CMS, with Lung Qi deficiency cold as the next frequently occurred type, while cases with fungus as the responsible sensitive allergens showed the pattern of Lung Qi deficiency cold as the most frequent pattern, with Kidney Yang insufficiency as the next frequently seen type, with obviously statistic significance among various CMS patterns (P<0.05). However, there was no markedly statistic significance among various Chinese Medicine patterns (P>0.05) for cases with animal fur as their responsible sensitive allergens.Conclusions There is certain association of responsible sensitive allergens with attacking of AR in autumn as well as its CMS manifestation. This association will be helpful to CMS differentiation for making up therapeutic strategy foe such a condition in clinical practice.