CAJ | 학술논문

目的：研究 CD90和血管内皮生长因子（VEGF）在肝细胞癌组织中的表达及其临床意义。方法利用免疫组化法检测33例肝细胞癌手术切除标本、25例癌旁组织标本和20例正常肝脏组织标本中 CD90和 VEGF 的表达情况。结果肝细胞癌组织中 CD90、VEGF 的阳性表达率分别为72.73%和81.82%，高于癌旁组织（48.00%和52.00%）和正常肝脏组织（0.00%和45.00%）（P <0.05）。结论 CD90和 VEGF 表达与肝细胞癌的发生、发展关系密切。
목적：연구 CD90화혈관내피생장인자（VEGF）재간세포암조직중적표체급기림상의의。방법이용면역조화법검측33례간세포암수술절제표본、25례암방조직표본화20례정상간장조직표본중 CD90화 VEGF 적표체정황。결과간세포암조직중 CD90、VEGF 적양성표체솔분별위72.73%화81.82%，고우암방조직（48.00%화52.00%）화정상간장조직（0.00%화45.00%）（P <0.05）。결론 CD90화 VEGF 표체여간세포암적발생、발전관계밀절。
Objective To investigate the expressions and clinical significance of CD90 and vascular endothelial growth factor(VEGF)in the hepatocellular carcinoma. Methods Immunohistochemistry was used to detect the ex-pressions of CD90 and VEGF in the 33 cases of hepatocellular carcinoma tissues,the 25 cases of paraneoplastic tis-sues and 20 cases of normal liver tissues. Results The positive expression rate of CD90 and VEGF in the hepato-cellular carcinoma tissues(72. 73% and 81. 82% )were higher than those in the paraneoplastic tissues(48. 00%and 52. 00% )and the normal liver tissues(0. 00% and 45. 00% )(P < 0. 05). Conclusion The expressions of CD90 and VEGF are closely related to the canceration and development of hepatocellular carcinoma.