中国感染控制杂志
中國感染控製雜誌
중국감염공제잡지
CHINESE JOURNAL OF INFECTION CONTROL
2014年
4期
242-245
,共4页
多重耐药菌%医院感染%监测%感染控制%抗药性,微生物
多重耐藥菌%醫院感染%鑑測%感染控製%抗藥性,微生物
다중내약균%의원감염%감측%감염공제%항약성,미생물
multidrug-resistant organism%healthcare-associated infection%monitor%infection control%drug-re-sistance,microbial
目的:了解某院多重耐药菌的临床分布特点,以采取针对性的预防控制措施。方法回顾性分析该院2012年1月1日-12月31日检出的891株多重耐药菌监测资料。结果891株多重耐药菌中,以产超广谱β-内酰胺酶(ESBLs)的大肠埃希菌居首位(342株,38.39%),其次为产ESBLs肺炎克雷伯菌(195株,21.89%)、多重耐药鲍曼不动杆菌(185株,20.76%)、耐甲氧西林金黄色葡萄球菌(138株,15.49%)、多重耐药铜绿假单胞菌(27株,3.03%)、产ESBLs奇异变形杆菌(2株,0.22%)、产ESBLs产酸克雷伯菌(2株,0.22%);主要集中在综合重症监护室(ICU;163株,18.29%)、神经内科(136株,15.26%)、普通外科(103株,11.56%)、神经外科(85株,9.54%)和呼吸内科(71株,7.97%)。痰标本分离多重耐药菌最多的是多重耐药鲍曼不动杆菌(242株,50.63%),主要集中在综合ICU;尿标本分离最多的是产ESBLs大肠埃希菌(141株,80.57%),主要集中在神经内科和泌尿外科。结论该院多重耐药菌感染部位主要为下呼吸道和泌尿系统;应加强对高危科室和易感人群的监控,制定有针对性的预防控制措施,遏制多重耐药菌的感染和传播。
目的:瞭解某院多重耐藥菌的臨床分佈特點,以採取針對性的預防控製措施。方法迴顧性分析該院2012年1月1日-12月31日檢齣的891株多重耐藥菌鑑測資料。結果891株多重耐藥菌中,以產超廣譜β-內酰胺酶(ESBLs)的大腸埃希菌居首位(342株,38.39%),其次為產ESBLs肺炎剋雷伯菌(195株,21.89%)、多重耐藥鮑曼不動桿菌(185株,20.76%)、耐甲氧西林金黃色葡萄毬菌(138株,15.49%)、多重耐藥銅綠假單胞菌(27株,3.03%)、產ESBLs奇異變形桿菌(2株,0.22%)、產ESBLs產痠剋雷伯菌(2株,0.22%);主要集中在綜閤重癥鑑護室(ICU;163株,18.29%)、神經內科(136株,15.26%)、普通外科(103株,11.56%)、神經外科(85株,9.54%)和呼吸內科(71株,7.97%)。痰標本分離多重耐藥菌最多的是多重耐藥鮑曼不動桿菌(242株,50.63%),主要集中在綜閤ICU;尿標本分離最多的是產ESBLs大腸埃希菌(141株,80.57%),主要集中在神經內科和泌尿外科。結論該院多重耐藥菌感染部位主要為下呼吸道和泌尿繫統;應加彊對高危科室和易感人群的鑑控,製定有針對性的預防控製措施,遏製多重耐藥菌的感染和傳播。
목적:료해모원다중내약균적림상분포특점,이채취침대성적예방공제조시。방법회고성분석해원2012년1월1일-12월31일검출적891주다중내약균감측자료。결과891주다중내약균중,이산초엄보β-내선알매(ESBLs)적대장애희균거수위(342주,38.39%),기차위산ESBLs폐염극뢰백균(195주,21.89%)、다중내약포만불동간균(185주,20.76%)、내갑양서림금황색포도구균(138주,15.49%)、다중내약동록가단포균(27주,3.03%)、산ESBLs기이변형간균(2주,0.22%)、산ESBLs산산극뢰백균(2주,0.22%);주요집중재종합중증감호실(ICU;163주,18.29%)、신경내과(136주,15.26%)、보통외과(103주,11.56%)、신경외과(85주,9.54%)화호흡내과(71주,7.97%)。담표본분리다중내약균최다적시다중내약포만불동간균(242주,50.63%),주요집중재종합ICU;뇨표본분리최다적시산ESBLs대장애희균(141주,80.57%),주요집중재신경내과화비뇨외과。결론해원다중내약균감염부위주요위하호흡도화비뇨계통;응가강대고위과실화역감인군적감공,제정유침대성적예방공제조시,알제다중내약균적감염화전파。
Objective To realize the characteristics of clinical distribution of multidrug-resistant organisms (MDRO)in a hospital,and take specific measures for the prevention and control of infection.Methods Surveillance data of 891 MDR isolates detected in a hospital between January 1 and December 31,2012 were analyzed retrospec-tively.Results Of 891 MDR isolates,extended-spectrumβ-lactamase (ESBL)-producing Escherichiacoli ranked first(342,38.39% ),followed by ESBL-producing Klebsiellapneumoniae(195,21.89% ),MDRAcinetobacterbau-mannii(185,20.76% ),methicillin-resistantStaphylococcusaureus(138,15.49% ),MDRPseudomonasaeruginosa (27,3.03% ),ESBL-producingProteusmirabilis(2,0.22% ),and ESBL-producing Klebsiellaoxytoca(2,0.22% );Bacteria mainly concentrated on general intensive care unit(ICU)(163,18.29% ),department of neurology(136, 15.26% ),general surgery(103,11.56% ),neurosurgery(85,9.54% ),and respiratory diseases department(71, 7.97% ).The most common bacteria isolated from sputum was MDR Acinetobacterbaumannii(242,50.63% ),and mainly concentrated on general ICU;the most common bacteria isolated from urine was ESBL-producing Escherich-iacoli(141 ,80.57% ),mainly concentrated on the departments of neurology and urology. Conclusion MDRO infec-tion in this hospital mainly concentrate on lower respiratory tract and urinary system. Monitor on high-risk depart-ments and vulnerable patients should be intensified,targeted preventive measures should be stressed to curb MDRO infection and spread.