中国感染控制杂志
中國感染控製雜誌
중국감염공제잡지
CHINESE JOURNAL OF INFECTION CONTROL
2014年
4期
239-241
,共3页
鲍曼不动杆菌%医院感染%ICU%抗菌药物%抗药性,微生物%耐药%多重耐药
鮑曼不動桿菌%醫院感染%ICU%抗菌藥物%抗藥性,微生物%耐藥%多重耐藥
포만불동간균%의원감염%ICU%항균약물%항약성,미생물%내약%다중내약
Acinetobacterbaumannii%healthcare-associated infection%intensive care unit%antimicrobial agent%drug resistance,microbial%drug resistance%multidrug resistance
目的：了解鲍曼不动杆菌在不同病区的医院感染现状及耐药性差异，为有效预防及治疗医院鲍曼不动杆菌感染提供依据。方法回顾性分析某院2012年1月-2013年7月住院患者送检标本中分离的446株鲍曼不动杆菌资料。结果446株鲍曼不动杆菌主要分离自重症监护室（ICU；236株，52．92％），其次是呼吸内科（55株，12．33％）和神经外科（48株，10．76％）；均主要来源于痰标本（共占94．62％）。13种常用抗菌药物的药敏结果显示，ICU分离的鲍曼不动杆菌耐药性最强，其敏感率均＜20％；神经外科分离株耐药性次之，敏感率均＜30％；而呼吸内科分离株敏感率均＞50％，耐药率最低。结论不同病区分离的鲍曼不动杆菌耐药性差异较大，ICU分离株耐药性最严重。
目的：瞭解鮑曼不動桿菌在不同病區的醫院感染現狀及耐藥性差異，為有效預防及治療醫院鮑曼不動桿菌感染提供依據。方法迴顧性分析某院2012年1月-2013年7月住院患者送檢標本中分離的446株鮑曼不動桿菌資料。結果446株鮑曼不動桿菌主要分離自重癥鑑護室（ICU；236株，52．92％），其次是呼吸內科（55株，12．33％）和神經外科（48株，10．76％）；均主要來源于痰標本（共佔94．62％）。13種常用抗菌藥物的藥敏結果顯示，ICU分離的鮑曼不動桿菌耐藥性最彊，其敏感率均＜20％；神經外科分離株耐藥性次之，敏感率均＜30％；而呼吸內科分離株敏感率均＞50％，耐藥率最低。結論不同病區分離的鮑曼不動桿菌耐藥性差異較大，ICU分離株耐藥性最嚴重。
목적：료해포만불동간균재불동병구적의원감염현상급내약성차이，위유효예방급치료의원포만불동간균감염제공의거。방법회고성분석모원2012년1월-2013년7월주원환자송검표본중분리적446주포만불동간균자료。결과446주포만불동간균주요분리자중증감호실（ICU；236주，52．92％），기차시호흡내과（55주，12．33％）화신경외과（48주，10．76％）；균주요래원우담표본（공점94．62％）。13충상용항균약물적약민결과현시，ICU분리적포만불동간균내약성최강，기민감솔균＜20％；신경외과분리주내약성차지，민감솔균＜30％；이호흡내과분리주민감솔균＞50％，내약솔최저。결론불동병구분리적포만불동간균내약성차이교대，ICU분리주내약성최엄중。
Objective To investigate the difference in healthcare-associated infection (HAI)status and antimicro-bial resistance of Acinetobacterbaumannii(A.baumannii)isolated from different wards,so as to provide evidence for effective prevention and therapy for HAI caused by A.baumannii.Methods Clinical data of 446 A.baumannii isolates from hospitalized patients between January 2012 and July 2013 were analyzed retrospectively. Results The majority of 446 A.baumanniiisolates were from patients admitted to intensive care unit (ICU,n= 236,52.92% ), followed by departments of respiratory diseases(n= 55,12.33% )and neurosurgery (n= 48,10.76% ),and the strains were mainly isolated from sputum specimens (94.62% ).Antimicrobial susceptibility testing with 13 kinds of commonly used antimicrobial agents showed that antimicrobial resistance of A.baumanniifrom ICU were highest, susceptibility rates were all<20% ,the next were from department of neurosurgery,susceptibility rates were all<30% ,while susceptibility rates of A.baumanniifrom department of respiratory diseases were all >50% .Conclu-sion The difference in antimicrobial resistance of A.baumanniifrom different wards varied significantly,antimi-crobial resistance of A.baumanniifrom ICU is most serious.
