CAJ | 학술논문

目的：分析儿童颅咽管瘤患儿眼部改变的特点。方法回顾性系列病例研究。收集2011年9月至2012年5月在首都医科大学附属北京天坛医院治疗的17例（34只眼）儿童颅咽管瘤患者的临床资料，对患儿术前矫正视力、视野、视乳头改变、肿瘤生长部位及肿瘤大小等进行分析。结果患儿年龄5～14岁，平均（10.3±3.2）岁，男女性别之比为1.83∶1，患病高峰年龄集中在8～12岁；视力下降眼占79.41％（27/34）。眼底视乳头改变者占44.12％（15/34），其中视乳头水肿占5.9％（2/34），视神经萎缩占32.35％（11/34），视乳头色淡占5.9％（2/34）。视野缺损占76.47％（26/34）。肿瘤大小与视野改变之间差异无统计学意义（P＞0.05）。结论儿童颅咽管瘤患者视力及视野的受损程度比眼底视乳头改变更明显和严重。
목적：분석인동로인관류환인안부개변적특점。방법회고성계렬병례연구。수집2011년9월지2012년5월재수도의과대학부속북경천단의원치료적17례（34지안）인동로인관류환자적림상자료，대환인술전교정시력、시야、시유두개변、종류생장부위급종류대소등진행분석。결과환인년령5～14세，평균（10.3±3.2）세，남녀성별지비위1.83∶1，환병고봉년령집중재8～12세；시력하강안점79.41％（27/34）。안저시유두개변자점44.12％（15/34），기중시유두수종점5.9％（2/34），시신경위축점32.35％（11/34），시유두색담점5.9％（2/34）。시야결손점76.47％（26/34）。종류대소여시야개변지간차이무통계학의의（P＞0.05）。결론인동로인관류환자시력급시야적수손정도비안저시유두개변경명현화엄중。
Objective To analyze the characteristics of ocular changes in children craniopharyngioma.Methods Retrospective case series study.The clinical data of 34 eyes from 17 patients with children craniopharyngioma treated at the affiliated Beijing Tiantan Hospital , Capital Medical University from September 2011 to May 2012 were collected.Records of preoperative clinical examinations including best corrected visual acuity ( BCVA ) , visual field test , optic disc findings , size and location of the tumor were analyzed.Results The age of the patients was from 5 to 14 years old [mean (10.29 ±3.22) years] with the male/female ratio of 1.83∶1.The most affected age group was 8 to 12 years old.Deficits in BCVA occurred in 79.41%(27/34).Abnormal optic disc findings occurred in 44.12%which included optic disk edema 5.9%(2/34), atrophic changes of the optic nerve 32.35% (11/34) and pale optic disc 5.9%(2/34).Various visual field defects were 76.47% (26/34).Conclusion Declines of visual acuities and defects of visual fields were more severe than optic disc damages in children patients with craniopharyngioma.