实用放射学杂志
實用放射學雜誌
실용방사학잡지
JOURNAL OF PRACTICAL RADIOLOGY
2014年
5期
736-739
,共4页
阳君%苏丹柯%刘丽东%谢东%金观桥%刘思远%黄伟丽
暘君%囌丹柯%劉麗東%謝東%金觀橋%劉思遠%黃偉麗
양군%소단가%류려동%사동%금관교%류사원%황위려
鼻咽癌%淋巴结%磁共振扩散加权成像
鼻嚥癌%淋巴結%磁共振擴散加權成像
비인암%림파결%자공진확산가권성상
nasopharyngeal carcinoma%lymph node%diffusion-weighted MRI
目的:探讨1.5T 磁共振扩散加权成像(diffusion-weighted imaging,DWI)对鼻咽癌颈部小淋巴结转移瘤的诊断价值,寻求鼻咽癌小淋巴结转移瘤的表观弥散系数(apparent diffusion coefficient,ADC)诊断阈值。方法收集经病理证实的40例鼻咽癌患者的颈部淋巴结 MRI 常规平扫、增强扫描及 DWI 影像学资料,分别测量颈部转移性大淋巴结组、转移性小淋巴结组和良性淋巴结组的 ADC 值,运用 SPSS16.0统计学软件对各组 ADC 值进行差异性分析,采用受试者工作特征(receiver operating characteris-tic,ROC)曲线确定鼻咽癌颈部小淋巴结转移瘤的 ADC 诊断阈值并研究其诊断效能。结果颈部转移性大淋巴结组和小淋巴结组ADC 值分别为(0.74±0.11)×10-3 mm2/s 和(0.75±0.13)×10-3 mm2/s,二者间差异无统计学意义(P >0.05);良性淋巴结组 ADC 值为(1.05±0.18)×10-3 mm2/s,与转移性小淋巴结组和转移性大淋巴结组 ADC 值差异均有统计学意义(P<0.05);以0.908×10-3 mm2/s作为鼻咽癌颈部小淋巴结转移瘤的 ADC 诊断阈值,其诊断特异性及敏感性分别为90.9%、83.2%,曲线下面积为0.92。结论MRI 扩散加权成像对鼻咽癌颈部小淋巴结转移瘤具有较高的诊断价值。
目的:探討1.5T 磁共振擴散加權成像(diffusion-weighted imaging,DWI)對鼻嚥癌頸部小淋巴結轉移瘤的診斷價值,尋求鼻嚥癌小淋巴結轉移瘤的錶觀瀰散繫數(apparent diffusion coefficient,ADC)診斷閾值。方法收集經病理證實的40例鼻嚥癌患者的頸部淋巴結 MRI 常規平掃、增彊掃描及 DWI 影像學資料,分彆測量頸部轉移性大淋巴結組、轉移性小淋巴結組和良性淋巴結組的 ADC 值,運用 SPSS16.0統計學軟件對各組 ADC 值進行差異性分析,採用受試者工作特徵(receiver operating characteris-tic,ROC)麯線確定鼻嚥癌頸部小淋巴結轉移瘤的 ADC 診斷閾值併研究其診斷效能。結果頸部轉移性大淋巴結組和小淋巴結組ADC 值分彆為(0.74±0.11)×10-3 mm2/s 和(0.75±0.13)×10-3 mm2/s,二者間差異無統計學意義(P >0.05);良性淋巴結組 ADC 值為(1.05±0.18)×10-3 mm2/s,與轉移性小淋巴結組和轉移性大淋巴結組 ADC 值差異均有統計學意義(P<0.05);以0.908×10-3 mm2/s作為鼻嚥癌頸部小淋巴結轉移瘤的 ADC 診斷閾值,其診斷特異性及敏感性分彆為90.9%、83.2%,麯線下麵積為0.92。結論MRI 擴散加權成像對鼻嚥癌頸部小淋巴結轉移瘤具有較高的診斷價值。
목적:탐토1.5T 자공진확산가권성상(diffusion-weighted imaging,DWI)대비인암경부소림파결전이류적진단개치,심구비인암소림파결전이류적표관미산계수(apparent diffusion coefficient,ADC)진단역치。방법수집경병리증실적40례비인암환자적경부림파결 MRI 상규평소、증강소묘급 DWI 영상학자료,분별측량경부전이성대림파결조、전이성소림파결조화량성림파결조적 ADC 치,운용 SPSS16.0통계학연건대각조 ADC 치진행차이성분석,채용수시자공작특정(receiver operating characteris-tic,ROC)곡선학정비인암경부소림파결전이류적 ADC 진단역치병연구기진단효능。결과경부전이성대림파결조화소림파결조ADC 치분별위(0.74±0.11)×10-3 mm2/s 화(0.75±0.13)×10-3 mm2/s,이자간차이무통계학의의(P >0.05);량성림파결조 ADC 치위(1.05±0.18)×10-3 mm2/s,여전이성소림파결조화전이성대림파결조 ADC 치차이균유통계학의의(P<0.05);이0.908×10-3 mm2/s작위비인암경부소림파결전이류적 ADC 진단역치,기진단특이성급민감성분별위90.9%、83.2%,곡선하면적위0.92。결론MRI 확산가권성상대비인암경부소림파결전이류구유교고적진단개치。
Objective To study the diagnostic value of 1.5T diffusion-weighted magnetic resonance imaging for small metastatic cervical lymph nodes of nasopharyngeal carcinoma(NPC),and to explore the optimal diagnostic threshold value of apparent diffusion coefficient(ADC)in small metastatic cervical lymph nodes of NPC.Methods 40 patients with histopathologically confirmed NPC were underwent conventional,enhanced and DWI MR.The mean ADC value of large metastatic cervical lymph nodes group,small metastatic cervical lymph nodes group and benign lymph nodes group were measured respectively.Statistical analysis was done by using the SPSS 1 6.0 program software.The receiver operating characteristic (ROC)curve was performed to obtain the ADC thresh-old value of small metastatic cervical lymph nodes and the diagnostic efficacy.Results The mean ADC value of large metastatic cer-vical lymph nodes group was (0.74±0.1 1)×10 -3 mm2/s,which was not significantly different from that in small metastatic cervical lymph nodes group(0.75±0.13)×10 -3 mm2/s,P >0.05.The mean ADC value in benign lymph nodes group was (1.05± 0.18)× 10 -3 mm2/s,which was significantly higher than that in large metastatic cervical lymph nodes group and small metastatic cervical lymph nodes group(P <0.05 ).Using a threshold ADC value of 0.908 × 10 -3 mm2/s for differentiating small metastatic cervical lymph nodes from benign lymph nodes,a sensitivity of 83.2% and specificity of 90.9% were obtained,the area under the ROC curve was 0.92.Conclusion DWI is helpful in the diagnosis of small metastatic cervical lymph nodes of NPC.