CAJ | 학술논문

目的探讨寿胎丸加味配合克罗米芬在干预肾虚型黄体功能不全性不孕(肾虚证)的临床疗效。方法将黄体功能不全性不孕(肾虚证)患者71例随机分为试验组(n=35)和对照组(n=36)。试验组于月经第5日起每日口服克罗米芬50mg,连用5天。同时于自基础体温上升起服用寿胎丸加味；对照组仅服用克罗米芬治疗,剂量及用法同试验组。观察两组治疗前后激素水平及中医症候改善情况。结果两组治疗前后比较中医证候疗效,试验组优于对照组,差异有显著性(P<0.05)；血清P、E2试验组高于对照组,血清T、PRL试验组低于对照组,差异均有显著性(P<0.05)。结论寿胎丸加味配合克罗米芬干预黄体功能不全性不孕症具有一定疗效。
목적탐토수태환가미배합극라미분재간예신허형황체공능불전성불잉(신허증)적림상료효。방법장황체공능불전성불잉(신허증)환자71례수궤분위시험조(n=35)화대조조(n=36)。시험조우월경제5일기매일구복극라미분50mg,련용5천。동시우자기출체온상승기복용수태환가미；대조조부복용극라미분치료,제량급용법동시험조。관찰량조치료전후격소수평급중의증후개선정황。결과량조치료전후비교중의증후료효,시험조우우대조조,차이유현저성(P<0.05)；혈청P、E2시험조고우대조조,혈청T、PRL시험조저우대조조,차이균유현저성(P<0.05)。결론수태환가미배합극라미분간예황체공능불전성불잉증구유일정료효。
Objective Discussion the effect of treating infertility due to luteal phase deficiency ( kidney deficiency type) by jia wei shou tai Pills with clomiphene. Method Dividing 71 cases treat infertility due to luteal phase defi-ciency (kidney deficiency type) randomly into experimental group (n=35) and control group (n=36). For experi-mental group give Clomiphene 50ml per day since the fifth day of menses in the continuous five days. Meanwhile take jia wei shou tai Pills since basical body temperature rise. While for control group only take clomiphene with the same amount comparied with experimental group. Result Compared with two groups, the disease and treatment difference have statistical significance, the experimental group is superior to the control group(P<0. 05). As for en-docrine hormones:on serum P、E2 , the experimental group is superior to the control group; on serum T、PRL, the experimental group is inferior to the control group. The differences have statistical significance(P<0. 05). Conclu-sion This research reveals that treating infertility due to luteal phase deficiency by jia wei shou tai Pills with clomi-phene has excellent effects.