CAJ | 학술논문

目的：对胰十二指肠切除术中胰管内放置引流管的随机对照试验（RCT）进行 Meta分析。方法计算机检索Cochrane图书馆、Medline、Embase、Cbmdisc的随机对照试验，利用统计软件为 Cochrane协作网提供的Revman4．2．10分析胰十二指肠切除术中胰管内放置引流管与不放置引流管在胰瘘发生率等方面的结果。结果通过阅读文献、全文，按照纳入排除标准和排除标准，筛选出3篇符合标准的RCT 542例患者。胰管内放置引流管组较不放置引流管组胰瘘发生率明显降低，差异有统计学意义（P ＝0．003），其他手术并发症、围手术期死亡率、住院时间方面差异无统计学意义。结论胰管内放置引流管能降低胰瘘发生率。
목적：대이십이지장절제술중이관내방치인류관적수궤대조시험（RCT）진행 Meta분석。방법계산궤검색Cochrane도서관、Medline、Embase、Cbmdisc적수궤대조시험，이용통계연건위 Cochrane협작망제공적Revman4．2．10분석이십이지장절제술중이관내방치인류관여불방치인류관재이루발생솔등방면적결과。결과통과열독문헌、전문，안조납입배제표준화배제표준，사선출3편부합표준적RCT 542례환자。이관내방치인류관조교불방치인류관조이루발생솔명현강저，차이유통계학의의（P ＝0．003），기타수술병발증、위수술기사망솔、주원시간방면차이무통계학의의。결론이관내방치인류관능강저이루발생솔。
Objective This study aimed to conduct a meta-analysis on the use of an external pancreatic duct stent after pancreaticoduodenectomy.Methods A comprehensive literature review research was carried out in the Cochrane Controlled Trials Register Databases,Medline and CBMdisc et al.and randomized con-trolled trials (RCTs)were adopted for analyses by Revman4.2.10.Results 3 RCTs including a total of 542 patients were selected and the meta-analysis revealed that the use of an external pancreatic duct stent was associated with a statistically significant reduction in overall PF (P =0.003);other postoperative compli-cations,mortality and hospital stay were not statistically different between the two groups.Conclusion The use of an external pancreatic duct stent was associated with a statistically significant reduction in overall PF.