中国医药
中國醫藥
중국의약
CHINA MEDICINE
2013年
8期
1144-1146
,共3页
蒋丽君%吴玉梅%兰晓玉%李晓燕
蔣麗君%吳玉梅%蘭曉玉%李曉燕
장려군%오옥매%란효옥%리효연
绝经期综合征%情志干预%中药疗法%Kupperman评分%性激素
絕經期綜閤徵%情誌榦預%中藥療法%Kupperman評分%性激素
절경기종합정%정지간예%중약요법%Kupperman평분%성격소
Menopausal syndrome%Emotional intervention%Therapy of traditional Chinese medicine%Kupperman score%Sex hormones
目的 探讨情志干预配合中药疗法治疗围绝经期综合征的疗效.方法 将65例围绝经期综合征患者完全随机分成2组.中药组(单纯中药治疗组)32例,采用单纯补肾中药治疗；联合组(中药+情志干预治疗组)33例,采用补肾中药治疗的基础上加情志干预治疗.2组疗程均为3个月.分别于治疗前后采用Kupperman改良记分法进行围绝经期综合征症状评分,并进行血清卵泡刺激素和雌激素水平检测.结果 中药组治疗过程中因不能坚持服药脱落3例,联合组治疗过程中因家庭原因及不能参加活动脱落2例.中药组总有效率为84.4％(27/32),联合组总有效率为90.9％(30/33),2组比较差异无统计学意义(P＞0.05).2组在潮热、出汗方面疗效相当(P＞0.05),联合组在失眠、焦虑、性交痛及泌尿系等症状改善方面明显优于中药组(P＜0.05).联合组治疗后雌激素水平较治疗前明显升高,差异有统计学意义[(59.1±3.3) mIU/L比(25.2±2.6)mIU/L](P＜0.05)；中药组治疗后雌激素水平与治疗前比较,差异无统计学意义(P＞0.05).2组治疗后,卵泡刺激素水平与治疗前比较差异无统计学意义(P＞0.05).结论 情志干预配合中药疗法能有效治疗围绝经期综合征,特别是能改善患者的神经精神症状和泌尿系症状.
目的 探討情誌榦預配閤中藥療法治療圍絕經期綜閤徵的療效.方法 將65例圍絕經期綜閤徵患者完全隨機分成2組.中藥組(單純中藥治療組)32例,採用單純補腎中藥治療；聯閤組(中藥+情誌榦預治療組)33例,採用補腎中藥治療的基礎上加情誌榦預治療.2組療程均為3箇月.分彆于治療前後採用Kupperman改良記分法進行圍絕經期綜閤徵癥狀評分,併進行血清卵泡刺激素和雌激素水平檢測.結果 中藥組治療過程中因不能堅持服藥脫落3例,聯閤組治療過程中因傢庭原因及不能參加活動脫落2例.中藥組總有效率為84.4％(27/32),聯閤組總有效率為90.9％(30/33),2組比較差異無統計學意義(P＞0.05).2組在潮熱、齣汗方麵療效相噹(P＞0.05),聯閤組在失眠、焦慮、性交痛及泌尿繫等癥狀改善方麵明顯優于中藥組(P＜0.05).聯閤組治療後雌激素水平較治療前明顯升高,差異有統計學意義[(59.1±3.3) mIU/L比(25.2±2.6)mIU/L](P＜0.05)；中藥組治療後雌激素水平與治療前比較,差異無統計學意義(P＞0.05).2組治療後,卵泡刺激素水平與治療前比較差異無統計學意義(P＞0.05).結論 情誌榦預配閤中藥療法能有效治療圍絕經期綜閤徵,特彆是能改善患者的神經精神癥狀和泌尿繫癥狀.
목적 탐토정지간예배합중약요법치료위절경기종합정적료효.방법 장65례위절경기종합정환자완전수궤분성2조.중약조(단순중약치료조)32례,채용단순보신중약치료；연합조(중약+정지간예치료조)33례,채용보신중약치료적기출상가정지간예치료.2조료정균위3개월.분별우치료전후채용Kupperman개량기분법진행위절경기종합정증상평분,병진행혈청란포자격소화자격소수평검측.결과 중약조치료과정중인불능견지복약탈락3례,연합조치료과정중인가정원인급불능삼가활동탈락2례.중약조총유효솔위84.4％(27/32),연합조총유효솔위90.9％(30/33),2조비교차이무통계학의의(P＞0.05).2조재조열、출한방면료효상당(P＞0.05),연합조재실면、초필、성교통급비뇨계등증상개선방면명현우우중약조(P＜0.05).연합조치료후자격소수평교치료전명현승고,차이유통계학의의[(59.1±3.3) mIU/L비(25.2±2.6)mIU/L](P＜0.05)；중약조치료후자격소수평여치료전비교,차이무통계학의의(P＞0.05).2조치료후,란포자격소수평여치료전비교차이무통계학의의(P＞0.05).결론 정지간예배합중약요법능유효치료위절경기종합정,특별시능개선환자적신경정신증상화비뇨계증상.
Objective To discuss the efficacy of modern intervention with traditional Chinese medicine therapy treating perimenopausal syndrome.Methods Seventy patients with perimenopausal syndrome were randomly divided into two groups.Group A of 32 cases were given with pure traditional Chinese medicine treatment; group B of 33 cases were given traditional Chinese medicine treatment and modern intervention therapy.A course was 3 months.Comprehensive curative effect was evaluated using Kupperman score.Condition of improvement of individual symptoms and serum hormone levels were observed before and after treatment.Results The total effective rate of group A was 84.4％ (27/32) ; the total effective rate of group B was 90.9％ (30/33).Two groups had no significant difference (P ＞ 0.05).Group A and group B had no significant difference in terms of hot flushes,sweating quite (P ＞ 0.05),efficacy in insomnia,anxiety,sexual intercourse pain and urinary symptoms.Compared with baseline levels,E2 level in group B after treatment had statistically significant difference [(59.1 ± 3.3) mIU/L vs (25.2 ± 2.6) mIU/L] (P ＜ 0.05) ; E2 levels after treatment group A had no significant difference (P ＞ 0.05) compared with baseline.Follicle-stimulating hormone levels in the two groups after treatment had no obvious difference compared with the baseline level (P ＞ 0.05).Conclusions Modern intervention with traditional Chinese medicine therapy is effective treatment of perimenopausal syndrome.It especially can improve surround vasomotor menopausal syndrome patients and neuropsychological symptoms.
