临床儿科杂志
臨床兒科雜誌
림상인과잡지
2014年
4期
352-354
,共3页
产单核细胞李斯特菌%脑膜炎%氨苄西林%氨基糖苷类%儿童
產單覈細胞李斯特菌%腦膜炎%氨芐西林%氨基糖苷類%兒童
산단핵세포리사특균%뇌막염%안변서림%안기당감류%인동
Listeria monocytogenes%meningitis%ampicillin%aminoglycoside%child
目的：总结单核细胞增多性李斯特菌（LM）脑膜炎患儿的临床特点及治疗转归。方法回顾性分析1例诊断为LM脑膜炎患儿的临床资料，并查阅文献。结果本例患儿以发热、头痛、呕吐起病，经阿莫西林/克拉维酸钾及头孢曲松抗感染治疗有效，脑脊液及血培养均为LM生长。查阅到17篇相关文献，共24例患儿，其中4例死亡，10例发生脑积水等，氨苄西林或联合使用氨基糖苷类抗生素治疗有效。结论 LM脑膜炎在免疫功能正常儿童发生率低，但病死率及后遗症发生率高。脑脊液和血培养有助于诊断。
目的：總結單覈細胞增多性李斯特菌（LM）腦膜炎患兒的臨床特點及治療轉歸。方法迴顧性分析1例診斷為LM腦膜炎患兒的臨床資料，併查閱文獻。結果本例患兒以髮熱、頭痛、嘔吐起病，經阿莫西林/剋拉維痠鉀及頭孢麯鬆抗感染治療有效，腦脊液及血培養均為LM生長。查閱到17篇相關文獻，共24例患兒，其中4例死亡，10例髮生腦積水等，氨芐西林或聯閤使用氨基糖苷類抗生素治療有效。結論 LM腦膜炎在免疫功能正常兒童髮生率低，但病死率及後遺癥髮生率高。腦脊液和血培養有助于診斷。
목적：총결단핵세포증다성리사특균（LM）뇌막염환인적림상특점급치료전귀。방법회고성분석1례진단위LM뇌막염환인적림상자료，병사열문헌。결과본례환인이발열、두통、구토기병，경아막서림/극랍유산갑급두포곡송항감염치료유효，뇌척액급혈배양균위LM생장。사열도17편상관문헌，공24례환인，기중4례사망，10례발생뇌적수등，안변서림혹연합사용안기당감류항생소치료유효。결론 LM뇌막염재면역공능정상인동발생솔저，단병사솔급후유증발생솔고。뇌척액화혈배양유조우진단。
Objective The clinical characteristics and treatment outcomes of Listeria monocytogenes (LM) meningitis were reviewed. Methods The clinical data of a case of LM meningitis were retrospectively analyzed and a literature review was performed. Results The child initially presenting with fever, headache and vomit was treated with amoxicillin/clavulanic acid and ceftriaxone and the treatment effect was obvious. Cerebrospinal fluid and blood cultures were LM positive. In 17 related arti-cles, a total of 24 children with LM meningitis were reviewed. Among them, 4 patients died and 10 had hydrocephalus. The treatment with either ampicillin alone or in combination with aminoglycoside was effective. Conclusions LM meningitis was rare in immunocompetent children, but has high rates of mortality and sequelae.
