CAJ | 학술논문

目的：评估射频消融术治疗合并重度肝硬化的小肝癌临床应用价值。方法连续收集合并重度肝硬化的小肝癌患者64例，根据治疗方式不同分为射频消融组和手术切除组。回顾性分析比较两组患者的临床疗效及术后并发症、复发转移率。结果两组之间年龄、性别、术前肝功能分级、1a后肿瘤复发转移率和生存率比较，无显著性差异（P＞0．05）。射频消融组手术时间、术中出血量、术后镇痛剂使用例数，住院时间均明显低于肝癌切除组（P＜0．05）。肝癌切除组术后出血、顽固性腹水、肝功能衰竭等并发症发生率明显高于射频消融组（P＜0．05）。结论合并重度肝硬化的小肝癌患者射频消融术的疗效与手术切除相当，且并发症少。
목적：평고사빈소융술치료합병중도간경화적소간암림상응용개치。방법련속수집합병중도간경화적소간암환자64례，근거치료방식불동분위사빈소융조화수술절제조。회고성분석비교량조환자적림상료효급술후병발증、복발전이솔。결과량조지간년령、성별、술전간공능분급、1a후종류복발전이솔화생존솔비교，무현저성차이（P＞0．05）。사빈소융조수술시간、술중출혈량、술후진통제사용례수，주원시간균명현저우간암절제조（P＜0．05）。간암절제조술후출혈、완고성복수、간공능쇠갈등병발증발생솔명현고우사빈소융조（P＜0．05）。결론합병중도간경화적소간암환자사빈소융술적료효여수술절제상당，차병발증소。
Objective 64 small liver cancer patients with severe cirrhosis were divided into two groups :the ra-diofrequency ablation group and cancer resection group .Retrospective analysis and comparison were carried out be-tween the two groups of patients with clinical efficacy ,postoperative complications and recurrence metastasis rate . Results Age ,gender ,liver function classification before operation ,tumor recurrence and metastasis rate and sur-vival rate after 1 years were similar in the two groups ( P>0 .05 ) .In the radiofrequency ablation group ,operation time ,intraoperative bleeding ,cases of using postoperative analgesic ,hospital stay were significantly lower than those of the cancer resection group ( P<0 .05 ) .Complications such as postoperative bleeding ,refractory ascites ,liv-er failure rate in cancer resection group were significantly higher than those of the radiofrequency ablation group (P<0 .05) .Conclusion The curative effect of radiofrequency ablation in treating small liver cancer patients with severe cirrhosis is similar to surgical resection ,and has fewer complications .