CAJ | 학술논문

目的：探讨生长抑素治疗肝硬化上消化道出血的临床疗效。方法将我院180例肝硬化上消化道出血患者分为治疗组和对照组各90例。治疗组采用生长抑素治疗，对照组采用垂体后叶素治疗。比较两组患者治疗的有效率和不良反应发生率。结果治疗组与对照组有效率分别为98.8％和57.8％，差异有统计学意义（χ2＝23.310，P＜0.05）；不良反应发生率分别为4.4％和22.2％，差异有统计学意义（χ2＝5.741，P＜0.05）。结论生长抑素治疗肝硬化上消化道出血能及时有效地挽救患者的生命，提高治疗有效率，降低不良反应发生率。
목적：탐토생장억소치료간경화상소화도출혈적림상료효。방법장아원180례간경화상소화도출혈환자분위치료조화대조조각90례。치료조채용생장억소치료，대조조채용수체후협소치료。비교량조환자치료적유효솔화불량반응발생솔。결과치료조여대조조유효솔분별위98.8％화57.8％，차이유통계학의의（χ2＝23.310，P＜0.05）；불량반응발생솔분별위4.4％화22.2％，차이유통계학의의（χ2＝5.741，P＜0.05）。결론생장억소치료간경화상소화도출혈능급시유효지만구환자적생명，제고치료유효솔，강저불량반응발생솔。
Objective To investigate the clinical efficiency of somatostatin in treatment of patients with upper gastrointestinal bleeding caused by cirrhosis .Methods One hundred eighty cases with upper gastrointestinal bleeding caused by cirrhosis in our hospi -tal were randomly divided into treatment and control groups .The treatment group was treated with somatostatin while the control group was treated with pituitrin .The effectiveness rate and the incidence of adverse reactions were compared between the two groups .Results The effective rate in the treatment group was 98.8%while 57.8%in the control group (χ2=23.310 ,P =0.000 ) .The incidence of adverse reactions was 4.4%in the treatment group while 22.2%in the control group(χ2=5.741,P =0.031).Conclusion Soma-tostatin can effectively save the patient's life,improve the treatment efficiency and reduce the incidence of adverse reactions in the treat -ment of upper gastrointestinal bleeding caused by cirrhosis .