医药前沿
醫藥前沿
의약전연
YIAYAO QIANYAN
2014年
7期
61-62
,共2页
低血糖症%脑损伤%新生儿%磁共振成像
低血糖癥%腦損傷%新生兒%磁共振成像
저혈당증%뇌손상%신생인%자공진성상
Hypoglycemia%Brain injuries%newborn%Magnetic resonance imaging
目的：探讨新生儿低血糖脑损伤的MRI特征及扩散加权成像(DWI)在低血糖脑损伤诊断中的应用价值。方法回顾性分析9例经临床确诊的新生儿低血糖脑损伤病例的MRI资料，所有病例均在出生后1～7d行MRI检查，扫描序列包括常规T1WI、T2WI及DWI序列。结果9例患儿血糖水平在0.2～1.8mmol/l,平均约0.95mmol/l。常规T1WI表现为受累部位稍低信号4例，稍高信号1例；7例T2WI表现为受累部位稍高信号或灰白质分界不清。9例行DWI扫描均发现斑片状、条状及脑回样高信号，其中受累部位双侧顶枕叶皮层及皮层下白质8例，胼胝体受累5例，侧脑室旁脑白质受累4例，基底核受累2例，尾状核头部受累1例，所有患儿小脑及脑干均未见异常。结论新生儿低血糖脑损伤以双侧枕顶叶后部脑组织及胼胝体压部最常受累，常对称性分布，具有一定特征性。DWI序列较常规T1WI及T2WI序列在低血糖脑损伤的诊断及评估上更具优越性。
目的：探討新生兒低血糖腦損傷的MRI特徵及擴散加權成像(DWI)在低血糖腦損傷診斷中的應用價值。方法迴顧性分析9例經臨床確診的新生兒低血糖腦損傷病例的MRI資料，所有病例均在齣生後1～7d行MRI檢查，掃描序列包括常規T1WI、T2WI及DWI序列。結果9例患兒血糖水平在0.2～1.8mmol/l,平均約0.95mmol/l。常規T1WI錶現為受纍部位稍低信號4例，稍高信號1例；7例T2WI錶現為受纍部位稍高信號或灰白質分界不清。9例行DWI掃描均髮現斑片狀、條狀及腦迴樣高信號，其中受纍部位雙側頂枕葉皮層及皮層下白質8例，胼胝體受纍5例，側腦室徬腦白質受纍4例，基底覈受纍2例，尾狀覈頭部受纍1例，所有患兒小腦及腦榦均未見異常。結論新生兒低血糖腦損傷以雙側枕頂葉後部腦組織及胼胝體壓部最常受纍，常對稱性分佈，具有一定特徵性。DWI序列較常規T1WI及T2WI序列在低血糖腦損傷的診斷及評估上更具優越性。
목적：탐토신생인저혈당뇌손상적MRI특정급확산가권성상(DWI)재저혈당뇌손상진단중적응용개치。방법회고성분석9례경림상학진적신생인저혈당뇌손상병례적MRI자료，소유병례균재출생후1～7d행MRI검사，소묘서렬포괄상규T1WI、T2WI급DWI서렬。결과9례환인혈당수평재0.2～1.8mmol/l,평균약0.95mmol/l。상규T1WI표현위수루부위초저신호4례，초고신호1례；7례T2WI표현위수루부위초고신호혹회백질분계불청。9례행DWI소묘균발현반편상、조상급뇌회양고신호，기중수루부위쌍측정침협피층급피층하백질8례，변지체수루5례，측뇌실방뇌백질수루4례，기저핵수루2례，미상핵두부수루1례，소유환인소뇌급뇌간균미견이상。결론신생인저혈당뇌손상이쌍측침정협후부뇌조직급변지체압부최상수루，상대칭성분포，구유일정특정성。DWI서렬교상규T1WI급T2WI서렬재저혈당뇌손상적진단급평고상경구우월성。
0bjective:To investigate MRI features of neonatal hypoglycemic brain injury(NHBI)and to explore the value of diffusion-weighted imaging (DWI)in the diagnosis of NHBI. Methods:MR imaging features of 9 neonates with NHB1 were retrospectively evaluated.Al the neoates were performed 1~7 days of life with MRI sequences including TlWI,T2WI and DWI.Results:The level of blood glucose was 0.2~ 1.8mmol/l in 9 cases of neonatal hypoglycemia,an average about 0.95mmol/1. NHBI showed slight hypointensity(4 cases) and slight hyperintensity(1 cases)on TlWI and hyperintense(7cases)and poor gray-white differentiation on T2WI. Al of the DWI imaging showed abnormalities;The parietal and occipital cortex and subcortical white matter abnornlalities occurred in 88.9%(8cases) of infants with hypoglycemia brain injury,corpus cal osum abnormalities occurred in 55.6%(5cases)of intants with hypoglycemia brain injury;the periventricular white matter injury occurred in 44.4%(4cases)of infants with hypoglycemia brain injury;22.2%(2cases)ofinfants with hypoglycemia had basal ganglia abnormalities,and 11.1% (1case)had head of caudate nucleus abmormality.There were no abnormal signal in cerebel um and brain stem in al cases.Conclusion:NHBI has some specific imaging features.Bilateral posterior parietal-occipital and the splenium of corpus cal osum are most likely to be injured in NHBI,which exhibits a more symmetric distribution.DWI is superior to TlWI and T2WI in the detection of NHBI.
