医药前沿
醫藥前沿
의약전연
YIAYAO QIANYAN
2014年
7期
22-23
,共2页
侯婷婷%谢萍%张文静%邓建君%马斌
侯婷婷%謝萍%張文靜%鄧建君%馬斌
후정정%사평%장문정%산건군%마빈
阻塞性睡眠呼吸暂停综合征%心肺系统疾病%脑血管疾病%情绪障碍和认知障碍%内分泌疾病
阻塞性睡眠呼吸暫停綜閤徵%心肺繫統疾病%腦血管疾病%情緒障礙和認知障礙%內分泌疾病
조새성수면호흡잠정종합정%심폐계통질병%뇌혈관질병%정서장애화인지장애%내분비질병
Obstructive sleep apnea syndrome%heart and lung system diseases%cerebrovascular diseases%mood disorder and cognitive impairment%endocrine diseases
目的:阻塞性睡眠呼吸暂停综合征(OSAS)是一种以睡眠状态下反复发生呼吸暂停和(或)低通气为主要表现的并发多系统疾病的临床综合征。近年研究表明,OSAS与心肺系统疾病,脑血管疾病(CVD),情绪障碍和认知障碍,内分泌疾病的发生联系密切,其机制可能与OSAS导致的低氧血症、高碳酸血症、炎症、氧化应激、自主神经功能紊乱、血管内皮功能紊乱等有关。
目的:阻塞性睡眠呼吸暫停綜閤徵(OSAS)是一種以睡眠狀態下反複髮生呼吸暫停和(或)低通氣為主要錶現的併髮多繫統疾病的臨床綜閤徵。近年研究錶明,OSAS與心肺繫統疾病,腦血管疾病(CVD),情緒障礙和認知障礙,內分泌疾病的髮生聯繫密切,其機製可能與OSAS導緻的低氧血癥、高碳痠血癥、炎癥、氧化應激、自主神經功能紊亂、血管內皮功能紊亂等有關。
목적:조새성수면호흡잠정종합정(OSAS)시일충이수면상태하반복발생호흡잠정화(혹)저통기위주요표현적병발다계통질병적림상종합정。근년연구표명,OSAS여심폐계통질병,뇌혈관질병(CVD),정서장애화인지장애,내분비질병적발생련계밀절,기궤제가능여OSAS도치적저양혈증、고탄산혈증、염증、양화응격、자주신경공능문란、혈관내피공능문란등유관。
Obstructive sleep apnea syndrome(OSAS)is characterized by repetitive apnea and/or hypopnea during sleep,and it can cause multisystem diseases.Recent researches have shown OSAS is closely correlated with heart and lung system diseases,cerebrovascular diseases, mood disorder and cognitive impairment,endocrine diseases.Its mechanisms may be related to hypoxemia,hypereapnia,inflammation,oxidative stress,and dysfunction of autonomic nerve and vascular endothelium caused by OSAS .