医药前沿
醫藥前沿
의약전연
YIAYAO QIANYAN
2014年
7期
19-20
,共2页
不孕%体外受精%胞浆内单精子注射%妊娠结局%回顾
不孕%體外受精%胞漿內單精子註射%妊娠結跼%迴顧
불잉%체외수정%포장내단정자주사%임신결국%회고
infertility%IVF%cytoplasmic sperm injection%pregnancy outcomes%Review
目的：探讨不孕患者应用体外受精/胞浆内单精子注射（IVF/ICSI）妊娠结局的回顾特点。方法本次选取100例接受IVF/ICSI助孕的不孕患者作研究对象，分析影响妊娠结局的因素。结果本次选择的100例不孕患者，年龄≤30岁50例，31-35岁40例，≥36岁10例。妊娠率分别为56%，47.5%，40%。总妊娠率为51%。显示随年龄增加，妊娠率呈下降趋势，年龄≤30岁妊娠率明显高于其它两组（P<0.05）。继发不孕54例，原发不孕46例，前者妊娠率为51.8%，50%，组间比较无明显差异（P>0.05）。卵巢功能低下占1%，排卵巢障碍占5%，输卵管因素占85%，其它因素占9%。非条件logistic回归分析显示，针对妊娠结局，H C G日P值，用药方案，B M I为危险因素（β>0，O R>1），而内膜厚度、即往妊娠史、总优胚数、M2卵泡数为保护因素（β<0，O R<1）。超排方案中，短方案组10例，长方案组90例，妊娠率分别为30%，70%，差异有统计学意义（P<0.05）。结论影响IVF/ICSI妊娠结局的因素较多，针对不孕接受IVF/ICSI助孕治疗的患者，获得成功妊娠为多因素共同作用结果，需建立个体化治疗方案，防范不良因素，以提高妊娠成功率，满足不孕患者的生育需求。
目的：探討不孕患者應用體外受精/胞漿內單精子註射（IVF/ICSI）妊娠結跼的迴顧特點。方法本次選取100例接受IVF/ICSI助孕的不孕患者作研究對象，分析影響妊娠結跼的因素。結果本次選擇的100例不孕患者，年齡≤30歲50例，31-35歲40例，≥36歲10例。妊娠率分彆為56%，47.5%，40%。總妊娠率為51%。顯示隨年齡增加，妊娠率呈下降趨勢，年齡≤30歲妊娠率明顯高于其它兩組（P<0.05）。繼髮不孕54例，原髮不孕46例，前者妊娠率為51.8%，50%，組間比較無明顯差異（P>0.05）。卵巢功能低下佔1%，排卵巢障礙佔5%，輸卵管因素佔85%，其它因素佔9%。非條件logistic迴歸分析顯示，針對妊娠結跼，H C G日P值，用藥方案，B M I為危險因素（β>0，O R>1），而內膜厚度、即往妊娠史、總優胚數、M2卵泡數為保護因素（β<0，O R<1）。超排方案中，短方案組10例，長方案組90例，妊娠率分彆為30%，70%，差異有統計學意義（P<0.05）。結論影響IVF/ICSI妊娠結跼的因素較多，針對不孕接受IVF/ICSI助孕治療的患者，穫得成功妊娠為多因素共同作用結果，需建立箇體化治療方案，防範不良因素，以提高妊娠成功率，滿足不孕患者的生育需求。
목적：탐토불잉환자응용체외수정/포장내단정자주사（IVF/ICSI）임신결국적회고특점。방법본차선취100례접수IVF/ICSI조잉적불잉환자작연구대상，분석영향임신결국적인소。결과본차선택적100례불잉환자，년령≤30세50례，31-35세40례，≥36세10례。임신솔분별위56%，47.5%，40%。총임신솔위51%。현시수년령증가，임신솔정하강추세，년령≤30세임신솔명현고우기타량조（P<0.05）。계발불잉54례，원발불잉46례，전자임신솔위51.8%，50%，조간비교무명현차이（P>0.05）。란소공능저하점1%，배란소장애점5%，수란관인소점85%，기타인소점9%。비조건logistic회귀분석현시，침대임신결국，H C G일P치，용약방안，B M I위위험인소（β>0，O R>1），이내막후도、즉왕임신사、총우배수、M2란포수위보호인소（β<0，O R<1）。초배방안중，단방안조10례，장방안조90례，임신솔분별위30%，70%，차이유통계학의의（P<0.05）。결론영향IVF/ICSI임신결국적인소교다，침대불잉접수IVF/ICSI조잉치료적환자，획득성공임신위다인소공동작용결과，수건립개체화치료방안，방범불량인소，이제고임신성공솔，만족불잉환자적생육수구。
Objective: To investigate the characteristics of sperm injection Review (IVF / ICSI) in the infertile patients with IVF / ICSI pregnancy outcome. Methods: The 100 patients to receive IVF / ICSI progesterone infertility patients for the study, analysis of factors affecting the outcome of pregnancy. Result: The selected 100 cases of infertility patients, aged ≤ 30 years old 50 cases 40 cases ,31-35 years, ≥ 36 years of age in 10 cases. Pregnancy rates were 56%, 47.5%, 40%. The total pregnancy rate was 51%. Show with increasing age, pregnancy declined, age ≤ 30 years of age pregnancy rate was significantly higher than the other two groups (P <0.05). Secondary infertility in 54 cases, 46 cases of primary infertility, pregnancy former 51.8%, 50%, no significant difference (P> 0.05) between the two groups. 1% of ovarian dysfunction, ranked ovarian disorders accounted for 5%, 85% tubal factor, other factors accounted for 9%. Unconditional logistic regression analysis showed that for the pregnancy outcome, HCG Day P values regimen, BMI is a risk factor (β> 0, OR> 1), and endometrial thickness, that is, to pregnancy history, the total number of quality embryo, M2 fol icles number of protective factors (β <0, OR <1). Superovulation scheme, the short program group 10 cases, 90 cases of long protocol group, the pregnancy rate was 30%, 70%, the difference was statistical y significant (P <0.05). Conclusion: The factors affecting IVF / ICSI pregnancy outcome more, IVF / ICSI treatment for infertility patients to receive progesterone, to be successful pregnancy is the result of many factors, the need to establish individualized treatment programs to prevent adverse factors, in order to improve pregnancy success rate, to meet the needs of fertility infertility patients.
