CAJ | 학술논문

RNA干扰（RNA interference，缩写为RNAi）是一种分子生物学上由双链RNA（dsRNA）诱发的基因沉默现象，该技术为农业害虫的防治开辟了一条新途径。从dsRNA导入方式、靶标基因选择、使用剂量及昆虫不同生长发育阶段4个方面阐述了其对RNAi技术的影响，介绍了国内外RNAi技术在农业生产中的应用情况，并探讨了昆虫RNAi的信号系统传递机制以及今后的研究方向。
RNA간우（RNA interference，축사위RNAi）시일충분자생물학상유쌍련RNA（dsRNA）유발적기인침묵현상，해기술위농업해충적방치개벽료일조신도경。종dsRNA도입방식、파표기인선택、사용제량급곤충불동생장발육계단4개방면천술료기대RNAi기술적영향，개소료국내외RNAi기술재농업생산중적응용정황，병탐토료곤충RNAi적신호계통전체궤제이급금후적연구방향。
Expressing of target genes on insects is effectively regulated by introducing exogenous artiifcial synthesis dsRNAs moleculars, RNA interference (RNAi). With the development of functional genomes on insects, RNAi as the strategy of controlling pests in agriculture becomes a promising measures. Here the advances in relative introduction methods, inlfuence factors, management effect as well as signal transduction of RNAi in insects were summarized, meanwhile the prospective of application in agriculture was described in the future.