CAJ | 학술논문

目的：探讨住院 COPD 患者合并慢性肾脏病的患病率及危险因素。方法对2012年1月至2013年11月住院确诊的 COPD 患者进行慢性肾脏病的患病率及危险因素回顾性调查。结果在资料完整的948例 COPD 患者人群中,慢性肾脏病总的患病率约为24.5%,COPD 合并慢性肾脏病组PaCO 2、吸烟指数、血尿酸水平、糖尿病及高血压病患病率较无合并慢性肾脏病组高,而 PaO 2、体质量指数较无合并慢性肾脏病组低,差异有统计学意义。COPD 患者合并慢性肾脏病与 COPD 严重程度分级无明显的相关性。经多因素 Logistic 回归分析表明：低氧血症、高碳酸血症、糖尿病、高血压病是 COPD合并慢性肾脏病的危险因素(OR 值分别为2.34、3.25、2.67和1.8,95% CI 分别为2.01~2.75、2.95~3.77、1.99~3.27、1.18~2.63,P 值均<0.05)。结论 COPD 合并慢性肾脏病的患病率高,低氧血症、高碳酸血症、糖尿病、高血压病是 COPD 合并慢性肾脏病的危险因素,应引起重视。
목적：탐토주원 COPD 환자합병만성신장병적환병솔급위험인소。방법대2012년1월지2013년11월주원학진적 COPD 환자진행만성신장병적환병솔급위험인소회고성조사。결과재자료완정적948례 COPD 환자인군중,만성신장병총적환병솔약위24.5%,COPD 합병만성신장병조PaCO 2、흡연지수、혈뇨산수평、당뇨병급고혈압병환병솔교무합병만성신장병조고,이 PaO 2、체질량지수교무합병만성신장병조저,차이유통계학의의。COPD 환자합병만성신장병여 COPD 엄중정도분급무명현적상관성。경다인소 Logistic 회귀분석표명：저양혈증、고탄산혈증、당뇨병、고혈압병시 COPD합병만성신장병적위험인소(OR 치분별위2.34、3.25、2.67화1.8,95% CI 분별위2.01~2.75、2.95~3.77、1.99~3.27、1.18~2.63,P 치균<0.05)。결론 COPD 합병만성신장병적환병솔고,저양혈증、고탄산혈증、당뇨병、고혈압병시 COPD 합병만성신장병적위험인소,응인기중시。
Objective To investigate the prevalence and risk factors of the hospitalized patients with chronic obstructive pulmonary disease (COPD)combined with chronic kidney disease.Methods Investigate the prevalence and risk factors of chronic kidney disease of the patients diagnosed as COPD between January 2012 and November 2013 in the outpatient retrospectively.Results Among 948 cases of patients with COPD that having complete data,the overall prevalence of chronic kidney disease was about 24.5%.To COPD combined with chronic kidney disease group,the PaCO 2 ,smoking index,blood uricacid level,and the prevalence rate of diabetes and hypertension were higher than those of COPD without chronic kidney disease group,but PaO 2 ,body mass index were lower than those of COPD without chronic kidney disease group,the differences were statistically significant.COPD patients combined with chronic kidney disease with COPD severity classification had no obvious correlation.The multi-factor Logistic regression analysis showed that the hypoxemia,hypercapnia,diabetes,hypertension were risk factors for COPD combined with chronic kidney disease (OR values were 2.34,3.25,2.67 and 1.8,95% CI were 2.01~2.75,2.95~3.77,1.99~3.27,1.18~2.63,all P <0.05).Conclusions The prevalence of COPD combined with chronic kidney disease is high,hypoxemia,hypercapnia,diabetes and hypertension are risk factors for COPD combined with chronic kidney disease,which should be taken into consideration seriously.