CAJ | 학술논문

目的：探讨Fahr病和Fahr综合征的临床类型和影像学特点。方法对12例经头颅CT证实的Fahr病和Fahr综合征患者的临床表现及钙化分布特点进行分析。结果患者钙化多局限于双侧苍白球以内，临床多无症状和体征；钙化范围可扩大到脑叶或小脑等，临床多表现为头痛头晕、震颤、肢体活动受限、言语不清、痴呆等。结论 Fahr病和Fahr综合征基底节钙化出现的临床症状取决于受损部位，多与神经元损害的程度有关。
목적：탐토Fahr병화Fahr종합정적림상류형화영상학특점。방법대12례경두로CT증실적Fahr병화Fahr종합정환자적림상표현급개화분포특점진행분석。결과환자개화다국한우쌍측창백구이내，림상다무증상화체정；개화범위가확대도뇌협혹소뇌등，림상다표현위두통두훈、진전、지체활동수한、언어불청、치태등。결론 Fahr병화Fahr종합정기저절개화출현적림상증상취결우수손부위，다여신경원손해적정도유관。
Objective To explore clinical types and imaging characteristics of of Fahr disease and Fahr syndrome .Methods Clinical manifestations and calcifica-tion distribution characteristics were analyzed for 12 patients with Fahr disease and Fahr syndrome confirmed by brain CT .Results Most of calcification were within the limits of bilater-al globus pallidus ,patients had no symptoms and signs clinically ;calcification could extend to hemicere-brum ,cerebellum and so on ,at this time main clinical manifestations were headache/dizziness ,tremor , limited limbs activities ,slurred speech ,dementia and so on .Conclusion Clinical symptoms of basal gan-glia calcification of Fahr disease and Fahr syndrome depend on lesion sites and most are related to the de-gree of neuron lesion .