CAJ | 학술논문

目的：探讨酒精依赖患者出现震颤谵妄症状与血生化指标变化的相关性。方法将出现震颤谵妄症状的26例酒精依赖患者设为A组，未出现震颤谵妄症状的133例酒精依赖患者设为B组，对两组各项生化指标进行检测分析。结果 A组门冬氨酸氨基转移酶、γ-谷氨酰转肽酶、Ca＋水平显著高于B组，肌酐、K＋、Na＋、Cl-水平显著低于B组，差异均有显著或极显著性（P＜0．5或0．01）；Logisitic回归分析显示，当血清尿酸异常，γ-谷氨酰转肽酶＞371 U · L -1时，低K＋、低Na＋时震颤谵妄症状出现的危险性增大。结论监测血生化相关指标对预防酒精依赖患者出现震颤谵妄症状具有重要指导意义。
목적：탐토주정의뢰환자출현진전섬망증상여혈생화지표변화적상관성。방법장출현진전섬망증상적26례주정의뢰환자설위A조，미출현진전섬망증상적133례주정의뢰환자설위B조，대량조각항생화지표진행검측분석。결과 A조문동안산안기전이매、γ-곡안선전태매、Ca＋수평현저고우B조，기항、K＋、Na＋、Cl-수평현저저우B조，차이균유현저혹겁현저성（P＜0．5혹0．01）；Logisitic회귀분석현시，당혈청뇨산이상，γ-곡안선전태매＞371 U · L -1시，저K＋、저Na＋시진전섬망증상출현적위험성증대。결론감측혈생화상관지표대예방주정의뢰환자출현진전섬망증상구유중요지도의의。
Objective To investigate the correlation between delirium tremens (DT) and biochemical indi-cator changes in patients with alcohol dependence (AD) .Methods Twenty-six AD patients with DT were assigned to group A and 133 ones without to B ,all biochemical indicators of both groups contrastively and correlatively analyzed .Results Aspartate aminotransferase (AST ) ,γ-glutamyltranspeptidase (GGT ) and Ca+ level were significantly higher and creatinine ,K+ ,Na+ and Cl- lower in group A than B ,differences were significant or very significant (P<0 .05 or 0 .01);logistic regression analyses showed that DT risk increased when serum uric acid was abnormality ,GGT >371mmol/L ,K+ and Na+ low .Conclusion Mo-nitoring related blood biochemical indicators has important guiding significance for preventing DT develop-ment of AD patients .