CAJ | 학술논문

缺血性卒中最常见的病因是动脉粥样硬化，颈动脉粥样硬化斑块的破裂可导致卒中事件的发生。斑块内的复杂结构特征与斑块的易损性相关。斑块内新生血管是斑块发展和不稳定性增加的危险因素之一。因此，正确认识斑块内新生血管的病因和发病机制，以及与斑块稳定性之间的关系，有利于早期发现颈动脉粥样硬化并正确评估其稳定程度及破裂风险，对于预防和治疗卒中具有重要意义。
결혈성졸중최상견적병인시동맥죽양경화，경동맥죽양경화반괴적파렬가도치졸중사건적발생。반괴내적복잡결구특정여반괴적역손성상관。반괴내신생혈관시반괴발전화불은정성증가적위험인소지일。인차，정학인식반괴내신생혈관적병인화발병궤제，이급여반괴은정성지간적관계，유리우조기발현경동맥죽양경화병정학평고기은정정도급파렬풍험，대우예방화치료졸중구유중요의의。
The most common cause of ischemic stroke is atherosclerosis, the rupture of carotid atherosclerotic plaque is responsible for most clinical symptoms of stroke. Evidence has shown the correlation between compositional features and plaque vulnerability. Observational studies identify neovascularization as a risk factor in atherosclerotic plaque growth and destabilization. Therefore, the correct understanding of the etiology and pathogenesis of neovascularization could lead to a more accurate plaque vulnerability assessment, the therapy of neovascularization is signiifcant for the treatment and prevention of stroke.