CAJ | 학술논문

目的对不存在基础疾病、手术时间＜3h的甲状腺切除术患者围手术期是否需要使用抗菌药物预防手术部位感染(surgical site infection,SSI)进行探讨.方法 2047例行甲状腺切除术患者分为未使用预防性抗菌药物组(no-prophylactic antibiotic therapy,no-pABX) 1030例,使用预防性抗菌药物组(prophylactic antibiotic therapy,pABX) 1017例进行比较.结果两组手术时间分别为20 ～ 390 min和30 ～320 min,两组术后的SSI发生率均为0.1％；两组的手术时间和术后并发症比较差异无统计学意义(P＞0.05).结论甲状腺切除术为清洁类切口,同时也具有手术时间短、出血少和术后并发SSI极低等特点.如术中严格遵守无菌原则和采用精细的操作技术,围手术期不预防性使用抗菌药物仍然是安全的.
목적 대불존재기출질병、수술시간＜3h적갑상선절제술환자위수술기시부수요사용항균약물예방수술부위감염(surgical site infection,SSI)진행탐토.방법 2047례행갑상선절제술환자분위미사용예방성항균약물조(no-prophylactic antibiotic therapy,no-pABX) 1030례,사용예방성항균약물조(prophylactic antibiotic therapy,pABX) 1017례진행비교.결과 량조수술시간분별위20 ～ 390 min화30 ～320 min,량조술후적SSI발생솔균위0.1％；량조적수술시간화술후병발증비교차이무통계학의의(P＞0.05).결론 갑상선절제술위청길류절구,동시야구유수술시간단、출혈소화술후병발SSI겁저등특점.여술중엄격준수무균원칙화채용정세적조작기술,위수술기불예방성사용항균약물잉연시안전적.
Objective To analyze whether prophylactic antibiotic administration is necessary for the prevention of incision infection in patients undergoing thyroidectomy,a procedure that lasts less than 3 hours.Methods The clinical data of 2047 patients undergoing thyroidectomy were retrospectively analyzed.1030 cases did not undergo prophylactic antibiotic therapy in perioperation.1017 cases received prophylactic antibiotic therapy perioperatively.Results The operation time ranged from 20 min to 390 min in no-pABX group and that ranged from 30 min to 330 min in pABX group.Surgical site infection (SSI)developed respectively in 0.1％ in both the two groups.There were no significant differences in operation times and post-operative complications (P ＞ 0.05).Conclusions Classified as clear incision,SSI in thyroidectomy is rare,perioperative routine prophylactic antibiotic administration is unnecessary.