CAJ | 학술논문

目的：探讨经颅多普勒超声声学造影（contrast transcranial Doppler ，cTCD）在神经科常见疾病或综合征病因诊断中的应用价值。方法回顾性分析西安交通大学第一附属医院神经内科2013-03-2013-10237例门诊和住院患者以及41例青年志愿者cTCD结果和临床诊断的相关性。结果 cTCD阳性提示心脏右向左分流或卵圆孔未闭（patent foramen ovale ， PFO ），在神经科常见疾病或综合征中的阳性率分别为：偏头痛52％，晕厥50％，T IA 40％，眩晕32％，脑梗死29％，其中偏头痛组、晕厥组cTCD阳性率明显高于对照组（P＜0.01、P＜0.05）。结论 cTCD在偏头痛、晕厥中的阳性率高，对神经科常见疾病或综合征的病因诊断提供线索，可作为一项简便安全的筛查手段。
목적：탐토경로다보륵초성성학조영（contrast transcranial Doppler ，cTCD）재신경과상견질병혹종합정병인진단중적응용개치。방법회고성분석서안교통대학제일부속의원신경내과2013-03-2013-10237례문진화주원환자이급41례청년지원자cTCD결과화림상진단적상관성。결과 cTCD양성제시심장우향좌분류혹란원공미폐（patent foramen ovale ， PFO ），재신경과상견질병혹종합정중적양성솔분별위：편두통52％，훈궐50％，T IA 40％，현훈32％，뇌경사29％，기중편두통조、훈궐조cTCD양성솔명현고우대조조（P＜0.01、P＜0.05）。결론 cTCD재편두통、훈궐중적양성솔고，대신경과상견질병혹종합정적병인진단제공선색，가작위일항간편안전적사사수단。
Objective To explore the clinical value of con-trast transcranial Doppler (cTCD ) in etiology diagnosis for the common neurological disease or syndromes. Methods The subjects were consisted of 237 hospitalized or clinic patients and 41 health volunteers ,which consecutively enrolled in neurology department from March 2013 to October 2013 ,the first affiliated hospital of xi'an Jiaotong university.The cTCD examination results and final diagnosis of all subjects were retrospectively ana-lyzed among different groups. Results The cTCD examination positive means there exists right -to -left shunt or PFO in heart. The positive rate was 52% in migraine group ,50% in syncope group ,40% in TIA group ,32% in dizziness group and 29% in cerebral infarction group ,respectively.The positive rate in migraine and syncope group was significantly higher than those in normal controls(P<0.01 ,P<0.05). Conclusion cTCD positive rate is considerably high and to imply potential etiol-ogy in migraine and syncope patients. Therefore ,cTCD test could be recommended as a routine screening test for common neu-rological syndrome or disorders.