CAJ | 학술논문

目的：评价百生肼、利福喷汀治疗复治涂阳肺结核的疗效。方法选取本科2005-2011年收治的复治涂阳肺结核患者60例，以异烟肼、利福平、乙胺丁醇、吡嗪酰胺和链霉素治疗为标准组，以百生肼、利福喷汀、乙胺丁醇、吡嗪酰胺和链霉素治疗为非标准组。观察两组治疗后痰菌阴转率和病灶吸收总有效率情况。结果治疗2、5、8月末痰菌阴转，标准组分别为10例（33.3%）、13例（43.3%）、16例（53.3%）；而非标准组为18例（60.0%）、22例（73.3%）、26例（86.7%），两组比较差异有统计学意义（P ＜0.05）。疗程结束后，X 线胸片吸收情况，标准组总有效率63.3%（19/30），非标准组总有效率86.7%（26/30），两组比较差异有统计学意义（ P ＜0.05）。结论百生肼、利福喷汀治疗复治涂阳肺结核，痰菌阴转率和病灶吸收总有效率较优。
목적：평개백생정、리복분정치료복치도양폐결핵적료효。방법선취본과2005-2011년수치적복치도양폐결핵환자60례，이이연정、리복평、을알정순、필진선알화련매소치료위표준조，이백생정、리복분정、을알정순、필진선알화련매소치료위비표준조。관찰량조치료후담균음전솔화병조흡수총유효솔정황。결과치료2、5、8월말담균음전，표준조분별위10례（33.3%）、13례（43.3%）、16례（53.3%）；이비표준조위18례（60.0%）、22례（73.3%）、26례（86.7%），량조비교차이유통계학의의（P ＜0.05）。료정결속후，X 선흉편흡수정황，표준조총유효솔63.3%（19/30），비표준조총유효솔86.7%（26/30），량조비교차이유통계학의의（ P ＜0.05）。결론백생정、리복분정치료복치도양폐결핵，담균음전솔화병조흡수총유효솔교우。
Objective To evaluate the curative effect of pasliniazid,rifapentine treating recurrent smear - positive pulmonary tuberculosis. Methods 60 cases of recurrent smear - positive pulmonary tuberculosis from 2005 to 2011,30 cases were treated with isoniazid,rifampicin,ethambutol,pyrazinamide and streptomycin were selected as standard group,30 cases were treated with pasliniazid, rifapentine ethambutol, pyrazinamide and streptomycin were selected as non - standard group. Rate of phlegm germ feminine changed and lesions absorption rate the two groups after treatment were observed. Results 2,5,8 months after treatment,the rate of phlegm germ feminine changed,standard group were 33. 3% (10 / 30),43. 3%(13 / 30),53. 3% (16 / 30);Non - standard group were 60. 0% (18 / 30),73. 3% (22 / 30),86. 7% (26 / 30). The differences were statiscally significant(P < 0. 05). After treatment,lesion absorption rate of non - standard group was 86. 7%(26 / 30),the standard group was 63. 3% (19 / 30),the difference was statistically significant(P < 0. 05). Conclusion Rate of phlegm germ feminine change and lesions absorption rate of pasliniazid,rifapentine treating recurrent smear - positive pulmonary tuberculosis are excellent.