神经药理学报
神經藥理學報
신경약이학보
Journal of Hebei North University(Medical Edition)
2013年
1期
37-47
,共11页
睡眠%学习%记忆%脑电图%长时程增强
睡眠%學習%記憶%腦電圖%長時程增彊
수면%학습%기억%뇌전도%장시정증강
sleep%learning%memory%electroencephalography%long-term potentiation
学习后睡眠有利于记忆巩固,学习的类型不同,睡眠依赖的记忆巩固机制可能也有所不同,涉及到不同脑区在不同的睡眠时相的生理功能。睡眠有助于长时程增强(long-term potentiation,LTP)的形成,进而促进记忆的巩固。总睡眠剥夺、快动眼睡眠剥夺、片段性睡眠可以通过不同的分子生物学机制损伤记忆巩固。
學習後睡眠有利于記憶鞏固,學習的類型不同,睡眠依賴的記憶鞏固機製可能也有所不同,涉及到不同腦區在不同的睡眠時相的生理功能。睡眠有助于長時程增彊(long-term potentiation,LTP)的形成,進而促進記憶的鞏固。總睡眠剝奪、快動眼睡眠剝奪、片段性睡眠可以通過不同的分子生物學機製損傷記憶鞏固。
학습후수면유리우기억공고,학습적류형불동,수면의뢰적기억공고궤제가능야유소불동,섭급도불동뇌구재불동적수면시상적생리공능。수면유조우장시정증강(long-term potentiation,LTP)적형성,진이촉진기억적공고。총수면박탈、쾌동안수면박탈、편단성수면가이통과불동적분자생물학궤제손상기억공고。
Delayed post learning sleep but not wakefulness enhances memory consolidation. Different types of learning have unique sleep-related memory consolidation mechanisms that act in dissociable brain regions during different sleep phases throughout the night. Sleep exerts beneficial effect on memory consolidation by improving formation of long-term potentiation. Total sleep deprivation, rapid eye movement sleep deprivation and sleep fragmentation may lead to memory deficits through different molecular mechanisms.