中国保健营养(上旬刊)
中國保健營養(上旬刊)
중국보건영양(상순간)
China Health Care & Nutrition
2014年
1期
210-210,211
,共2页
脑白质病变%老年抑郁症
腦白質病變%老年抑鬱癥
뇌백질병변%노년억욱증
White matter lesions%Late life depression
目的:探讨脑白质病变与老年抑郁症的关系及临床表现。方法随机抽取120例WML患者,分为Ⅰ度、Ⅱ度、Ⅲ度,并选取30例非 WML的作为对照,均进行抑郁自评量表筛查,再进一步行汉密尔顿抑郁量表评分。结果Ⅰ度抑郁发生率为54.7%;Ⅱ度72.1%;Ⅲ度92.0%,WML的严重程度与老年抑郁的发生呈正相关,差异有统计学意义(χ2=6.51,P<0.05)。Ⅱ度、Ⅲ度患者的HAMD评分均高于Ⅰ度及对照组,在抑郁情绪、躯体性焦虑、精神性焦虑、睡眠障碍、全身症状、能力减退方面的评分显著有统计学差异(P<0.01)。结论 WML程度及部位和 LLD有一定相关性,其病变的程度与 HAMD评分及抑郁症的发生率呈正相关;伴程度不同的WML的LLD患者其临床表现不同。
目的:探討腦白質病變與老年抑鬱癥的關繫及臨床錶現。方法隨機抽取120例WML患者,分為Ⅰ度、Ⅱ度、Ⅲ度,併選取30例非 WML的作為對照,均進行抑鬱自評量錶篩查,再進一步行漢密爾頓抑鬱量錶評分。結果Ⅰ度抑鬱髮生率為54.7%;Ⅱ度72.1%;Ⅲ度92.0%,WML的嚴重程度與老年抑鬱的髮生呈正相關,差異有統計學意義(χ2=6.51,P<0.05)。Ⅱ度、Ⅲ度患者的HAMD評分均高于Ⅰ度及對照組,在抑鬱情緒、軀體性焦慮、精神性焦慮、睡眠障礙、全身癥狀、能力減退方麵的評分顯著有統計學差異(P<0.01)。結論 WML程度及部位和 LLD有一定相關性,其病變的程度與 HAMD評分及抑鬱癥的髮生率呈正相關;伴程度不同的WML的LLD患者其臨床錶現不同。
목적:탐토뇌백질병변여노년억욱증적관계급림상표현。방법수궤추취120례WML환자,분위Ⅰ도、Ⅱ도、Ⅲ도,병선취30례비 WML적작위대조,균진행억욱자평량표사사,재진일보행한밀이돈억욱량표평분。결과Ⅰ도억욱발생솔위54.7%;Ⅱ도72.1%;Ⅲ도92.0%,WML적엄중정도여노년억욱적발생정정상관,차이유통계학의의(χ2=6.51,P<0.05)。Ⅱ도、Ⅲ도환자적HAMD평분균고우Ⅰ도급대조조,재억욱정서、구체성초필、정신성초필、수면장애、전신증상、능력감퇴방면적평분현저유통계학차이(P<0.01)。결론 WML정도급부위화 LLD유일정상관성,기병변적정도여 HAMD평분급억욱증적발생솔정정상관;반정도불동적WML적LLD환자기림상표현불동。
Objective To analyze of the relationship and clinical manifestations between WML and LLD .Methods 120 WML patients and 30 healthy subjects were enrolled.All they were screened using a SDS and those who with depression were further evaluated via HAMD .Results Incidence rate were54.7%,72.1%,and92.0%for three groups.Differences among the groups were statistically significant.(P<0.01).Conclusion Severity of depression might be correlated to severity,location,distri-bution of WML.Varying degrees of WML in LLD clinical manifestations are different .