CAJ | 학술논문

目的：定量分析病人静脉注射对比剂后生成的数字重组影像对射波刀颅骨追踪影像引导方式的影响。资料与方法选取41例采用射波刀治疗颅内肿瘤的病人，采用相同扫描参数行头部平扫CT和增强CT，分别生成基于上述CT的数字重组影像，并依次与病人治疗时采集的实时影像进行配准。增强CT和平扫CT配准后分别生成6个位置参量，对两组影像的各位置参量进行Pearson相关检验，并使用t检验定量分析两组配准结果。结果两组间各位置参量具有高度相关性，各位置参量间的偏差均值在±0.02 mm 之内，增强CT 组和平扫CT组相应位置参量的最大差异为0.3 mm，但该偏差无统计学意义（P>0.05）。结论是否使用对比剂对射波刀进行颅骨追踪的影像引导精度的影响非常小，差异远远小于系统误差，因此临床中该影响可以忽略不计。
목적：정량분석병인정맥주사대비제후생성적수자중조영상대사파도로골추종영상인도방식적영향。자료여방법선취41례채용사파도치료로내종류적병인，채용상동소묘삼수행두부평소CT화증강CT，분별생성기우상술CT적수자중조영상，병의차여병인치료시채집적실시영상진행배준。증강CT화평소CT배준후분별생성6개위치삼량，대량조영상적각위치삼량진행Pearson상관검험，병사용t검험정량분석량조배준결과。결과량조간각위치삼량구유고도상관성，각위치삼량간적편차균치재±0.02 mm 지내，증강CT 조화평소CT조상응위치삼량적최대차이위0.3 mm，단해편차무통계학의의（P>0.05）。결론시부사용대비제대사파도진행로골추종적영상인도정도적영향비상소，차이원원소우계통오차，인차림상중해영향가이홀략불계。
Objective To quantitatively evaluate the effect of using digitally reconstructed radiograph (DRR) generated images from contrast-enhanced CT on the accuracy of Cyberknife skull tracking. Methods Forty-one patients with intracranial lesions, planning to receive Cyberknife treatment, were enrolled. Each patient underwent CT with the same scanning parameters before and after administration of contract medium. For each patient 2 sets of DRR images (noncontrast, contrast) were generated as the references for the skull tracking image guided procedure. After image registering between DRR images and patients’ digital images generated by image guided system of Cyberknife, paired t-test was applied on the results. Results The deviations in 6 sets of position were all within ±0.02mm. The max deviation between the two reference groups was 0.3 mm. All of the results have no statistical differences (P>0.05). Conclusion Using contrast medium or not for generating reference has little effect on accuracy of Cyberknife skull tracking.