CAJ | 학술논문

目的：研究分析颅脑损伤术后肺部感染的相关危险因素。方法2008年1月～2013年10月期间收集我院治疗的1121例颅脑损伤手术患者，其中男性642例，女性479例；年龄19～72岁，平均（43.2±15.4）岁。根据是否合并肺部感染分为观察组与对照组，比较分析年龄、肺基础疾病、格拉斯哥昏迷（ GCS）评分、急性肺损伤、昏迷时间、卧床时间等因素。结果观察组年龄、肺基础疾病、GCS评分、急性肺损伤、昏迷时间、卧床时间与对照组相比较，差异均具有统计学意义（ P＜0.05）；但是两组性别比较差异无统计学意义（ P＞0.05）。观察组抗生素、抑酸剂、脱水剂、糖皮质激素等药物应用时间显著高于对照组，差异均具有统计学意义（P＜0.05）；但是观察组接受机械通气治疗的比例高于对照组，亦具有统计学意义（P＜0.05）。结论颅脑损伤术后肺部感染与多种危险因素相关，医护人员应提高认识，从而减少其危险因素，提高患者治疗质量和改善预后。
목적：연구분석로뇌손상술후폐부감염적상관위험인소。방법2008년1월～2013년10월기간수집아원치료적1121례로뇌손상수술환자，기중남성642례，녀성479례；년령19～72세，평균（43.2±15.4）세。근거시부합병폐부감염분위관찰조여대조조，비교분석년령、폐기출질병、격랍사가혼미（ GCS）평분、급성폐손상、혼미시간、와상시간등인소。결과관찰조년령、폐기출질병、GCS평분、급성폐손상、혼미시간、와상시간여대조조상비교，차이균구유통계학의의（ P＜0.05）；단시량조성별비교차이무통계학의의（ P＞0.05）。관찰조항생소、억산제、탈수제、당피질격소등약물응용시간현저고우대조조，차이균구유통계학의의（P＜0.05）；단시관찰조접수궤계통기치료적비례고우대조조，역구유통계학의의（P＜0.05）。결론로뇌손상술후폐부감염여다충위험인소상관，의호인원응제고인식，종이감소기위험인소，제고환자치료질량화개선예후。
Objective To study the relative risk factors of post-operative pulmonary infection after cranio-cerebral trauma .Methods Totally 1 121 craniocerebral trauma patients ,who received surgical treatments between Jan.2008 and Oct.2013,were divided into research group and control group depending on the existence of pulmona -ry infection.There were 642 males and 479 females,ranged with an average age of (43.2 ±15.4) years old(age ranged from 19 to 72 years old).The relative risk factors were analyzed .Results There were significant differ-ences in age ,lung underlying disease ,GCS score ,acute lung injury ,duration of coma and bed time between the two groups(P<0.05).However,there was no statistical difference in the gender between the two groups (P>0.05). In addition,the application time of antibiotics ,antacid,dehydrating agent ,and glucocorticoid and the application pro-portion of mechanical ventilation indicated statistical differences in comparison to the control group ( P <0.05 ) . Conclusion There are multi-risk factors relative to post-operative pulmonary infection after traumatic brain injury . Medical staffs should raise awareness so as to reduce these risk factors and to improve the therapeutic efficacy and prognosis .