CAJ | 학술논문

目的：探讨温经散寒通络汤联合针灸治疗类风湿性关节炎寒湿痹的临床疗效。方法：选择类风湿性关节炎寒湿痹患者88例，随机分为对照组和治疗组，对照组44例，给予口服双氯芬酸钠、柳氮磺胺吡啶、甲氨蝶呤；治疗组44例，在西药治疗基础上，加服温经散寒通络汤和针灸治疗。每组均治疗3个月，观察临床症状、体征和实验室指标改善情况。结果：两组在治疗前后比较，在临床症状、体征和实验室指标上均有较大改善（孕<0.05）；治疗组在改善休息痛、肿胀个数、肿胀指数、压痛个数、压痛指数、晨僵时间、肝肾功与对照组相比无统计学差异；与对照组比较，治疗组在改善关节功能障碍、双手握力及降低红细胞沉降率（ESR）、悦反应蛋白（CRP）、类风湿因子（RF）等有更明显的优势（孕<0.05）。结论：与单纯西药治疗相比，温经散寒通络汤联合针灸，结合西药治疗对类风湿性关节炎关节功能的改善、病情活动的控制有一定的优势。
목적：탐토온경산한통락탕연합침구치료류풍습성관절염한습비적림상료효。방법：선택류풍습성관절염한습비환자88례，수궤분위대조조화치료조，대조조44례，급여구복쌍록분산납、류담광알필정、갑안접령；치료조44례，재서약치료기출상，가복온경산한통락탕화침구치료。매조균치료3개월，관찰림상증상、체정화실험실지표개선정황。결과：량조재치료전후비교，재림상증상、체정화실험실지표상균유교대개선（잉<0.05）；치료조재개선휴식통、종창개수、종창지수、압통개수、압통지수、신강시간、간신공여대조조상비무통계학차이；여대조조비교，치료조재개선관절공능장애、쌍수악력급강저홍세포침강솔（ESR）、열반응단백（CRP）、류풍습인자（RF）등유경명현적우세（잉<0.05）。결론：여단순서약치료상비，온경산한통락탕연합침구，결합서약치료대류풍습성관절염관절공능적개선、병정활동적공제유일정적우세。
This study was aimed to explore clinical effect on treatment of rheumatoid arthritis (RA) of cold-dampness syndrome by the combination of Wen-Jing San-Han Tong-Luo (WJSHTL) decoction and acupuncture. A total of 88 RA patients were selected and randomly divided into the control group and the treatment group. All 44 cases in the control group were orally administrated with diclofenac sodium, sulphasalazine (SASP) and methotrexate (MTX). All 44 cases in the treatment group were treated with the combination of WJSHTL decoction and acupuncture on the ba-sis of western medication the same as the control group. Each group was treated for three months. Improvements of clinical symptoms, body signs and laboratory indexes were observed. The results showed that clinical symptoms, body signs and laboratory indexes were greatly improved in the comparison before and after treatment in both groups with statistical significance (P < 0.05). Compared to the control group, the treatment group had no statistical significance in the improvement of rest pain, swelling numbers and index, tenderness numbers and index, morning stiffness time, liver and kidney function. Compared with the control group, the treatment group had more obvious advantages in the improvement of joint function, hand grip strength, erythrocyte sedimentation rate (ESR) decreasing, C-reactive protein (CRP) and rheumatoid factor (P< 0.05). It was concluded that compared with single western medication, the combi-nation of WJSHTL decoction and acupuncture with western medication had certain advantages in the improvement of joint function of RA and management of patient's disease condition.