世界科学技术-中医药现代化
世界科學技術-中醫藥現代化
세계과학기술-중의약현대화
WORLD SCIENCE AND TECHNOLOGY-MODERNIZATION OF TRADITIONAL CHINESE MEDICINE
2014年
4期
743-748
,共6页
解毒通脉汤%闭塞性动脉硬化症%临床观察%因邪致瘀理论
解毒通脈湯%閉塞性動脈硬化癥%臨床觀察%因邪緻瘀理論
해독통맥탕%폐새성동맥경화증%림상관찰%인사치어이론
Jie-Du Tong-Mai decoction%arteriosclerosis obliterans%clinical observation%theory of evil causing stasis
目的：观察解毒通脉汤治疗闭塞性动脉硬化症的临床疗效。方法：选取246例闭塞性动脉硬化症患者中血脉瘀阻型患者，随机分成两组，对照组120例，患者常规口服拜阿司匹林0.1 g+辛伐他丁片20 mg ，每日一次；治疗组126例，患者在口服拜阿司匹林及辛伐他丁片的基础上，加服中药解毒通脉汤，8周后观察患者临床症状改善情况和臂踝指数（ABI）、超敏C反应蛋白（Hs-CRP）、持续经皮氧分压（TcPO2）变化。结果：与对照组相比，治疗组临床症状明显改善（P<0.05），患者ABI、CRP、TcPO2均有显著提高（P<0.01）。结论：解毒通脉汤对闭塞性动脉硬化症血脉瘀阻型患者治疗有效，间接验证了中医因邪致瘀理论的指导意义。
目的：觀察解毒通脈湯治療閉塞性動脈硬化癥的臨床療效。方法：選取246例閉塞性動脈硬化癥患者中血脈瘀阻型患者，隨機分成兩組，對照組120例，患者常規口服拜阿司匹林0.1 g+辛伐他丁片20 mg ，每日一次；治療組126例，患者在口服拜阿司匹林及辛伐他丁片的基礎上，加服中藥解毒通脈湯，8週後觀察患者臨床癥狀改善情況和臂踝指數（ABI）、超敏C反應蛋白（Hs-CRP）、持續經皮氧分壓（TcPO2）變化。結果：與對照組相比，治療組臨床癥狀明顯改善（P<0.05），患者ABI、CRP、TcPO2均有顯著提高（P<0.01）。結論：解毒通脈湯對閉塞性動脈硬化癥血脈瘀阻型患者治療有效，間接驗證瞭中醫因邪緻瘀理論的指導意義。
목적：관찰해독통맥탕치료폐새성동맥경화증적림상료효。방법：선취246례폐새성동맥경화증환자중혈맥어조형환자，수궤분성량조，대조조120례，환자상규구복배아사필림0.1 g+신벌타정편20 mg ，매일일차；치료조126례，환자재구복배아사필림급신벌타정편적기출상，가복중약해독통맥탕，8주후관찰환자림상증상개선정황화비과지수（ABI）、초민C반응단백（Hs-CRP）、지속경피양분압（TcPO2）변화。결과：여대조조상비，치료조림상증상명현개선（P<0.05），환자ABI、CRP、TcPO2균유현저제고（P<0.01）。결론：해독통맥탕대폐새성동맥경화증혈맥어조형환자치료유효，간접험증료중의인사치어이론적지도의의。
This study was aimed to observe the clinical efficacy of Jie-Du Tong-Mai (JDTM) decoction (i.e., detoxi-fication unclogg artery soup) of arteriosclerosis obliterans. A total of 246 arteriosclerosis obliterans cases with the pattern of blood stasis were selected and randomly divided into two groups. In the control group of 120 cases, 0.1 g of aspirin and 20 mg of simvastatin tablets were orally administrated, once a day. In the treatment group of 126 cas-es, JDTM decoction was combined on the basis of oral administration of aspirin and simvastatin tablets. After 8 weeks of treatment, observations were made on improvement of clinical symptoms and changes of ABI, Hs-CRP, TcpO2. The results showed that compared with the control group, clinical symptoms of the treatment group were obvi-ously improved (P< 0.05). And the ABI, CRP, TcpO2 were also obviously increased (P< 0.01). It was concluded that JDTM decoction was effective in the treatment of arteriosclerosis obliterans with the pattern of blood stasis. It al-so indirectly proved the guiding meaning of traditional Chinese medicine that evil causing stasis.
