CAJ | 학술논문

缓控释系统用于关节腔注射给药，可用于治疗类风湿性关节炎（ Rheumatoid Arthritis ，RA）和膝关节骨性关节炎（ Knee Os-teoarthritis，OA）等，除具有起效快，局部有效浓度高，不良反应小等优点外，还具有缓慢控制药物释放，延长药物作用时间，减少用药次数，提高药物安全性和有效性的作用。因此，药物缓控释系统在关节腔注射中具有广阔的应用前景。
완공석계통용우관절강주사급약，가용우치료류풍습성관절염（ Rheumatoid Arthritis ，RA）화슬관절골성관절염（ Knee Os-teoarthritis，OA）등，제구유기효쾌，국부유효농도고，불량반응소등우점외，환구유완만공제약물석방，연장약물작용시간，감소용약차수，제고약물안전성화유효성적작용。인차，약물완공석계통재관절강주사중구유엄활적응용전경。
Sustained and controlled release system for intra-articular injection can be used to treat diseases such as rheumatoid arthritis and knee osteoarthritis .It has many advantages , such as fast effect, high local effective concentration , little side effect, control the drug release slowly , prolongation of treatment , reduced frequency of administration , and improving safety and efficacy .Sustained and con-trolled release system for intra-articular injection has wide application prospect .