CAJ | 학술논문

目的：观察全身麻醉在艾滋病感染者手术中的安全性与可行性。方法选取22例实施全身麻醉的艾滋病感染者，通过对麻醉诱导期、维持期、拔管期的相关指标观察，与同期实施全身麻醉的22例非艾滋病感染者的麻醉效果进行比较。结果麻醉诱导期丙泊酚、舒芬太尼和顺式阿曲库铵的用药量按每公斤体重计算，维持期的用药量则按公斤体重时间计算，两组的丙泊酚、舒芬太尼和顺式阿曲库铵的用药量比较差异均无统计学意义(P>0.05)，麻醉过程中血管活性药物使用率(观察组2例，对照组3例)和拔管时间[观察组(15.54±4.24) min，对照组(15.00±4.08) min]比较差异均无统计学意义(P>0.05)。结论艾滋病患者在无症状期接受外科手术时，其对全身麻醉的耐受力与普通患者并无差异，艾滋病感染患者对全身麻醉的耐受性与其是否合并其他合并症和艾滋病发展的程度有关，与是否感染艾滋病病毒无关。
목적：관찰전신마취재애자병감염자수술중적안전성여가행성。방법선취22례실시전신마취적애자병감염자，통과대마취유도기、유지기、발관기적상관지표관찰，여동기실시전신마취적22례비애자병감염자적마취효과진행비교。결과마취유도기병박분、서분태니화순식아곡고안적용약량안매공근체중계산，유지기적용약량칙안공근체중시간계산，량조적병박분、서분태니화순식아곡고안적용약량비교차이균무통계학의의(P>0.05)，마취과정중혈관활성약물사용솔(관찰조2례，대조조3례)화발관시간[관찰조(15.54±4.24) min，대조조(15.00±4.08) min]비교차이균무통계학의의(P>0.05)。결론애자병환자재무증상기접수외과수술시，기대전신마취적내수력여보통환자병무차이，애자병감염환자대전신마취적내수성여기시부합병기타합병증화애자병발전적정도유관，여시부감염애자병병독무관。
Objective To observe the safety and feasibility of general anesthesia in patients with HIV. Methods Twenty-two patients with HIV undergoing general anesthesia were enrolled (AIDS group, the observa-tion group). Indicators were recorded at the induction, the maintenance and the extubation of anesthesia. The anes-thetic effect was compared with 22 patients with non-AIDS at the same period (non-AIDS group, the control group). Results There was no significant difference in the dosage of propofol, sufentanil cis-atracurium between the two groups during induction of anesthesia period (per kilogram of body weight,/kg) and the maintenance period [/(kg·h)], P>0.05. There was also no significant difference between the two groups in the vasoactive drugs used during anesthe-sia (2 patients in the observation group and 3 cases in the control group) and the extubation time [(15.54±4.24) min in the observation group and (15.00 ± 4.08) min in the control group], P>0.05. Conclusion Compared with non-AIDS patients, there was no significant difference in the tolerance of general anesthesia in patients with HIV in the aymptom-atic period. The tolerance of general anesthesia in patients with HIV is related to the other complications and the de-gree of AIDS, regardless of HIV infection.