CAJ | 학술논문

目的：探讨高压氧（ HBO）在难治性消化性溃疡治疗中的应用效果。方法回顾性分析259例难治性消化性溃疡患者的临床资料，根据是否行HBO治疗将患者分为高压氧组（127例）和对照组（132例）。比较两组总有效率、幽门螺杆菌（ Hp）根除率和复发率。结果高压氧组总有效率、Hp根除率分别为93．7％、92．1％，明显高于对照组的65．2％、56．1％（χ2＝31．97，7．32，均P＜0．05）；高压氧组复发率为8．4％，明显低于对照组的33．3％（χ2＝12．51，P＜0．05）。结论高压氧联合药物治疗难治性消化性溃疡具有更好的疗效。
목적：탐토고압양（ HBO）재난치성소화성궤양치료중적응용효과。방법회고성분석259례난치성소화성궤양환자적림상자료，근거시부행HBO치료장환자분위고압양조（127례）화대조조（132례）。비교량조총유효솔、유문라간균（ Hp）근제솔화복발솔。결과고압양조총유효솔、Hp근제솔분별위93．7％、92．1％，명현고우대조조적65．2％、56．1％（χ2＝31．97，7．32，균P＜0．05）；고압양조복발솔위8．4％，명현저우대조조적33．3％（χ2＝12．51，P＜0．05）。결론고압양연합약물치료난치성소화성궤양구유경호적료효。
Objective To explore the application effect of hyperbaric oxygen ( HBO ) in the treatment of refractory peptic ulcer .Methods Clinical data of 259 patients with refractory peptic ulcer were retrospectively ana-lyzed.According to whether received HBO therapy , these patients were divided into the HBO group ( n=127 ) and control group(n=132).The total effective rate,Helicobacter pylori(Hp) eradication rate and relapse rate of the two groups were compared .Results The total effective rate ,Hp eradication rate of the HBO group were 93.7%,92.1%, respectively,which were significantly higher than 65.2%,56.1% of the control group (χ2 =31.97,7.32,all P<0.05).The relapse rate of the HBO group was 8.4%,which was significantly lower than 33.3%of the control group (χ2 =12.51,P<0.05).Conclusion HBO combined with conventional drug in the treatment of refractory peptic ulcer has significant effect .