广东微量元素科学
廣東微量元素科學
엄동미량원소과학
GUANGDONG TRACE ELEMENTS SCIENCE
2014年
5期
18-21
,共4页
谭秀娟%薛晓英%卓海珍%曹殿青
譚秀娟%薛曉英%卓海珍%曹殿青
담수연%설효영%탁해진%조전청
血液稀释%脊柱手术%血小板功能
血液稀釋%脊柱手術%血小闆功能
혈액희석%척주수술%혈소판공능
normovolemic hemodulution%spine surgery%platelet function
目的:探讨急性等容性血液稀释( ANH)在脊柱手术中对患者血小板功能的影响。方法择期全麻下行脊柱手术患者20例,术前行颈内静脉穿刺采自体血,同时于外周静脉输入等量的胶体液(万汶),术中连续监测HR, SPO2, Bp 及尿量变化,分别于采血前( T0),采血后15 min (T1),输血前(T2),输血后15 min(T3),抽取桡动脉血查HB, HCT, LAC,并采用Sonoclot分析仪测定激活凝血酶原时间( ACT),凝血速率( CR),血小板功能( PF)。记录术中晶胶体液输入量,出血量和尿量。结果与T0相比, T1的HB, HCT显著下降(P<0.01), CR、 PF显著下降(P<0.01),与T2相比, T3的HB, HCT显著回升, CR、 PF显著升高(P<0.01), LAC, ACT变化无统计学意义。结论急性等容性血液稀释对脊柱手术患者血小板功能有一定的保护作用,对凝血功能无明显不良影响。
目的:探討急性等容性血液稀釋( ANH)在脊柱手術中對患者血小闆功能的影響。方法擇期全痳下行脊柱手術患者20例,術前行頸內靜脈穿刺採自體血,同時于外週靜脈輸入等量的膠體液(萬汶),術中連續鑑測HR, SPO2, Bp 及尿量變化,分彆于採血前( T0),採血後15 min (T1),輸血前(T2),輸血後15 min(T3),抽取橈動脈血查HB, HCT, LAC,併採用Sonoclot分析儀測定激活凝血酶原時間( ACT),凝血速率( CR),血小闆功能( PF)。記錄術中晶膠體液輸入量,齣血量和尿量。結果與T0相比, T1的HB, HCT顯著下降(P<0.01), CR、 PF顯著下降(P<0.01),與T2相比, T3的HB, HCT顯著迴升, CR、 PF顯著升高(P<0.01), LAC, ACT變化無統計學意義。結論急性等容性血液稀釋對脊柱手術患者血小闆功能有一定的保護作用,對凝血功能無明顯不良影響。
목적:탐토급성등용성혈액희석( ANH)재척주수술중대환자혈소판공능적영향。방법택기전마하행척주수술환자20례,술전행경내정맥천자채자체혈,동시우외주정맥수입등량적효체액(만문),술중련속감측HR, SPO2, Bp 급뇨량변화,분별우채혈전( T0),채혈후15 min (T1),수혈전(T2),수혈후15 min(T3),추취뇨동맥혈사HB, HCT, LAC,병채용Sonoclot분석의측정격활응혈매원시간( ACT),응혈속솔( CR),혈소판공능( PF)。기록술중정효체액수입량,출혈량화뇨량。결과여T0상비, T1적HB, HCT현저하강(P<0.01), CR、 PF현저하강(P<0.01),여T2상비, T3적HB, HCT현저회승, CR、 PF현저승고(P<0.01), LAC, ACT변화무통계학의의。결론급성등용성혈액희석대척주수술환자혈소판공능유일정적보호작용,대응혈공능무명현불량영향。
Objective To investigate the effect of acute normovolemic hemodilution on platelet function in patients undergoing spine surgery .Methods A total of twenty patients undergoing spine surgery were collected the autologous blood by internal jugular vein puncture before operation and the equivalent dose hydroxyethyl starch were infused at the same time .During the operation , the changes of HR , SPO2 , Bp and urine output were monitored .Then the changes of HCT , HB, LAC, ACT, CR, PF at 15 minutes before ( T0 ) and after ( T1 ) vein blood sampling , at 15 minutes before ( T2 ) and after ( T3 ) autotransfusion were monitored .Results Compare with T0, HB, HCT, CR, PF decreased at T1;Compare with T2, HB, HCT, CR, PF raised at T2.There were no statistically significant in LAC and ACT.Conclusion Platelet function could be shielded in patients with ANH undergoing spine surgery and no adverse effects on blood coagulation .